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Sleep apnoea likely caused by fatty tongues

14/01/2020

Sleep apnoea is a disorder that causes some individuals to experience pauses in their breathing while they are sleeping, resulting in them gasping for breath. Said pauses can last anywhere from a few seconds right up to a few minutes. But while sleep apnoea can be alleviated with certain measures, including wearing oral appliances at bedtime, its exact cause has remained open to debate. Now, a new study has revealed that having a fatty tongue could play a part. According to the research by a team from the Perelman School of Medicine in Philadelphia, larger, fattier tongues – which are more common among obese individuals – could be a main driver of sleep apnoea. That’s why when overweight and obese people shed the pounds, including fat in their tongues, any sleep apnoea they’ve been experiencing also tends to improve. “You talk, eat and breathe with your tongue - so why is fat deposited there?" said study author Dr Richard Schwab, of Perelman School of Medicine. “It's not clear why - it could be genetic or environmental - but the less fat there is, the less likely the tongue is to collapse during sleep.” The researchers now plan to discover which low-fat diets (if any) are particularly good at reducing fat in the tongue.

Could a simple skin patch effectively eliminate ‘love handles’?

19/09/2017

Whether you call them love handles or muffin tops, the areas of built up fat that can appear above your waistline are something that many people would love to be able to easily get rid of. A new patch developed by scientists in the US could provide the easy fix people have been looking for. The novel patch delivers fat-browning drugs directly into the areas of fat and converts "bad" white fat into "good" brown fat - not only reducing the amount of excess fat, but also lowering fasting blood glucose levels. Having too much white fat - particularly around the abdominal region - can raise the risk of several health problems, including diabetes and heart disease. So far, the patches have only been trialled on mice, but it’s hoped that they can be developed for human use in the future. Study co-leader Li Qiang, Ph.D., from the Columbia University Medical Center in New York City, said the patches could offer a great alternative to existing drugs that promote fat browning. Their non-invasive nature can reduce side effects. "The nanoparticles were designed to effectively hold the drug and then gradually collapse, releasing it into nearby tissue in a sustained way instead of spreading the drug throughout the body quickly," says study co-leader Zhen Gu, Ph.D., from the University of North Carolina at Chapel Hill and North Carolina State University in Raleigh.

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