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This cost effective, low-dose steroid could be a breakthrough treatment for COVID-19

18/06/2020

Experts in the UK say a cost effective and widely available drug can help save the lives of seriously ill COVID-19 patients. The drug, dexamethasone, a steroid, has been around since the early 1960s, and is usually given in low doses to patients with severe asthma, allergies and painful/swollen joints. It is also used to treat autoimmune conditions, such as systemic lupus erythematosus and rheumatoid arthritis. Dexamethasone’s effect on inflammation and our immune systems is what is believed to make it useful in treating patients with severe COVID-19 infections. The drug is part of the RECOVERY Trial, the largest clinical trial to date aiming to identify treatments that may be beneficial for COVID-19 patients. As part of the trial, researchers studied the effect of dexamethasone in 2,000 patients and compared that to the outcomes in 4,000 patients who did not receive it. Dexamethasone was found to cut the risk of death by a third for patients on ventilators. For those on oxygen, it cut deaths by a fifth. This equates to one life saved for every eight on ventilators and every 20-25 treated with oxygen. One of the biggest benefits of dexamethasone is that it is not cost prohibitive, meaning it could be pivotal for treating COVID-19 in poorer countries. [Related reading: What does it mean for a vaccine if the new coronavirus mutates?]

UK’s most Googled health questions of 2017 revealed

21/12/2017

Have you ever turned to Dr Google when you’ve been feeling under the weather? If you have, you’re not alone. Nowadays, tons of people research symptoms they’re experiencing on the world’s largest search engine. But while many of these searches confirm that the searcher is suffering from a common cold, others can see a simple sore throat query spiral off into diagnosing all sorts of rare conditions. It’s a reality that makes Googling health conditions both convenient and potentially terrifying. As the year draws to a close, the team at Google Trends has released information on the most popular heath questions people in the UK asked the search engine in 2017. Topping the list is the rather generic “why do I feel sick?” search. That’s followed by “why am I always tired?” and “what is cancer?” Have you ever heard of lupus? It seems many people have and want to know more about it, as “what is lupus?” is fourth on the list. This could be because pop icon Selena Gomez was diagnosed with lupus in 2015 and underwent surgery for the condition over the summer. Lupus is an autoimmune disease that causes sufferers to feel fatigued, have swollen or painful joints, and skin irritation or rashes. Because lupus is an autoimmune disease it is not contagious. More information about lupus, including warning signs, can be found on the NHS website. The final question completing the top five is “what is sepsis?” Sepsis is a life-threatening condition that can be triggered by an infection and leads to the body attacking its own organs and tissues. Sepsis can be treated with antibiotics if it is caught early enough and hasn’t already damaged any vital organs. More information about sepsis, including warning signs, can be found on the NHS website.

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