Cleveland Clinic has unveiled its top 10 medical innovations for 2021, and both telemedicine initiatives and app-connected health trackers feature. In fact, four medtech developments made the Cleveland Clinic list this year, underlining the importance of technology in healthcare. All of them were chosen in the belief they will be widely adopted in the coming year and have a significant clinical impact. Announced in conjunction with its annual Medical Innovation Summit, which is now in its 18th year, Cleveland Clinic’s top 10 innovations for this year were selected by a committee of subject matter experts at the academic medical center. This year, smartphone app-connected pacemakers were named the top medtech innovation because of their ability to better connect patients with their cardiac treatment, affording greater insights into the health data they produce. Bubble CPAP, a non-invasive ventilation strategy for premature babies, is the next medtech innovation on the Cleveland list. Bubble CPAP minimizes physical trauma and stimulates lung growth when administered over a prolonged period. Third on the list of medtech innovations is telemedicine, specifically increased access to these pivotal services through the removal of barriers. The fourth and final medtech innovation on the list is vacuum-induced uterine tamponade, a minimally invasive way for clinicians to stop postpartum hemorrhage (excessive bleeding after having a baby), which affects around one to five percent of women who give birth. The vacuum-induced device uses negative pressure created inside the uterus to collapse the bleeding cavity causing the muscle to close off the vessels. It’s a low-tech solution that could be taken advantage of in developing countries with low resource availability. [Related reading: What is telehealth?]
The United States Centers for Disease Control and Prevention (CDC) has previously recommended people wear cloth face coverings in public settings to reduce the spread of SARS-CoV-2. However, some people have been concerned about whether face coverings, such as masks, cause carbon dioxide (CO2) poisoning. Experts have now come out saying that’s impossible. Speaking about the use of cloth face masks, Prof Keith Neal, an infectious disease expert, said wearing one will not cause hypercapnia (too much carbon dioxide in the blood). Echoing these comments, Darrell Spurlock Jr., PhD, RN, the director of the Leadership Center for Nursing Education Research at Widener University, said: “Rebreathing tiny amounts of CO2 from wearing either properly fitted N95 respirators or more loosely fitted cloth or surgical masks is of no concern for the vast, vast majority of people.” Carbon dioxide molecules are tiny and do not get trapped by the breathable material used to make cloth ace masks. When you breathe out, the carbon dioxide goes through and round the mask. Surgeons and other medical professionals regularly wear much more heavy duty face coverings all day without coming to harm. Face masks can play a potentially important role in reducing the spread of SARS-CoV-2 because they can help limit it being transmitted by an infected individual. This is particularly true for people who are asymptomatic and do not actually know they have the virus. The only stipulation when it comes to the wearing of cloth face masks is that people with existing lung conditions should consult their physician before doing so. This is because masks do affect normal air entry and could make breathing difficult for people with severe lung diseases. [Related reading: COVID-19: Could a second wave already be here?]
The ongoing COVID-19 outbreak means many of us are spending a lot more time at home than we usually do. If you’re someone who enjoys regular trips to the gym, or jogs around your local park, you might be feeling decidedly antsy right now. But while social distancing measures and self-isolation means fewer opportunities to stay fit and active outdoors, there are ways you can maintain your physical and mental health while at home. Fortunately, there are a number of activities you can do at home that will satisfy the global recommendations for adults to accumulate at least 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity physical activity per week. Here are 5 ways to stay physically active in your own home: 1. Online yoga Yoga is great for both physical health and general wellness. It can also help relieve lower back and neck pain. The best part of all is you can practice it very easily and affordably at home. Just put some comfy clothes on and find a yoga channel you like on YouTube. 2. Simple resistance exercises If you haven’t got proper weights at home, no problem. Just be a little creative instead. Use a can of soup in each hand in place of dumbbells and do repetitions while sat comfortably on a chair. Find heavier objects if you want more resistance. 3. Basic calisthenics Calisthenics are exercises that require nothing more than your own body weight. So things like sit-ups, push-ups and pull-ups are all classed as calisthenics. If you want some additional encouragement, pull up a YouTube video and workout while watching it. 4. Home cardio Cardiovascular exercises work by increasing your heart rate for a short period of time. Examples of cardio exercises include running on the spot, jumping jacks, lunge jumps, and skipping in place. 5. Household chores Believe it or not, your household chores are a great way to get some exercise. Vacuuming and mopping floors is a great way to burn some calories, while removing laundry from the washing machine and hanging it out to dry gives your muscles a workout.
Several studies have revealed that COVID-19 is disproportionately impacting men and the potential reasons include everything from biology to bad habits. According to the World Health Organization, men have accounted for 69% of COVID-19 related deaths in Europe. Meanwhile, reports suggest that in New York City men have been dying from COVID-19 at almost twice the rate of women. It is thought that both genetics and lifestyle choices play a part when it comes to COVID-19 outcomes in men. First and foremost, because of their extra X chromosome, women have stronger immune systems and respond better to infections than men. Then there is the fact that more elderly men suffer from heart disease than elderly women and that high blood pressure and liver disease are more prevalent in men too. All of these conditions are factors that are associated with more negative COVID-19 outcomes. In addition, men are statistically more likely to smoke than women. In fact, according to Our World in Data figures, more than one-third (35%) of men in the world smoke, compared to just over 6% of women. With smoking one of the biggest risk factors for chronic lung disease, men are at a much greater disadvantage should they get COVID-19. [Related reading: Can you catch the new coronavirus twice?]
With news headlines currently dominated by the Covid-19 outbreak, it could be easy to overlook other health stories worthy of note. That’s why we are pleased to share that cancer rates in the United States are continuing to fall, according to a new report. As outlined in the Annual Report to the Nation on the Status of Cancer, cancer rates in the U.S. continued falling from 2001 to 2017 – dropping, on average, by 1.5% a year. Furthermore, new cancer diagnoses have decreased at an average annual rate of 0.6% over the same period. Interestingly, the annual decline in mortality was slightly more pronounced among men (1.8%) than women (1.4%); nevertheless, decreases were seen across all major racial/ethnic groups and among adults, teens and children alike. Among men, mortality rates fell for 11 of the 19 most common cancers. They remained stable for four cancers, including prostate. And increased for another four: mouth, pharynx, soft tissue and pancreas. Among women, mortality rates fell for 14 of the 20 most common cancers, including the top three: lung, breast and colon. However, an increase in mortality rates was seen in cancers of the uterus, liver, brain, soft tissue and pancreas. Mouth and pharynx cancer rates remained stable. Despite mortality rates decreasing by 4.8% a year in men and 3.7% in women, lung cancer remains the number one cause of cancer death in the United States. Commenting on the findings of the report, U.S. Centers for Disease Control director, Dr. Robert Redfield, said: “The United States continues to make significant progress in cancer prevention, early detection, and treatment.”
Gaining weight in later years has a detrimental impact on lung health, a new study suggests. People’s lungs naturally deteriorate as they age and lose functionality as the years go by. But now new research has linked moderate or significant weight gain to an even sharper decline in lung health. According to the study of 3,700 individuals in Europe and Australia, who were recruited between the ages of 20 and 44, and were studied for 20 years, people who gained weight throughout the course of the study – regardless of whether they were a healthy weight or overweight/obese to begin with – had accelerated lung function decline. Furthermore, overweight/obese individuals who lost weight during the study saw their lung functionality decline slow. Publishing their findings in the journal Thorax, the researchers said large amounts of fat in the abdomen and chest can limit the space lungs have when people inhale. It was also suggested that fat produces inflammatory chemicals that can reduce the diameter of airways and damage lungs. Speaking about the findings of the research, study leader Judith Garcia Aymerich, head of the non-communicable diseases and environment program at Barcelona Institute for Global Health (ISGlobal), said: “Although previous research has shown that weight gain is linked to lung function decline, ours is the first study to analyze such a varied population sample over a longer period of time.”
Lungs have the ability to repair themselves, but only if a person stops smoking, new research suggests. It had previously been thought that the mutations that lead to lung cancer were permanent and smokers had already done irreparable damage with their habits. However, the surprise findings, published in the journal Nature, show that some cells escape the damage caused by smoking and can actually help repair the cells around them once a person has quit. This almost magical ability was witnessed by scientists from the Wellcome Sanger Institute and UCL even in people who had smoked a pack a day for 40 years before giving up – highlighting that it’s really never too late to quit. Exactly how certain cells avoid the genetic devastation caused by smoking is unclear, but the researchers said they appeared to “exist in a nuclear bunker”. Speaking about the findings of the research, Dr Rachel Orritt, from Cancer Research UK, said: “It's a really motivating idea that people who stop smoking might reap the benefits twice over - by preventing more tobacco-related damage to lung cells, and by giving their lungs the chance to balance out some of the existing damage with healthier cells”. It is estimated that of the 47,000 cases of lung cancer in the UK each year, almost three-quarters are caused by smoking.
In 2018, there were nearly 50,000 confirmed cases of prostate cancer in England – around 8,000 more than in 2017, which makes it the most commonly diagnosed cancer in the country, overtaking breast cancer for the first time. Now Public Health England says that the reason why more cases of prostate cancer are being confirmed is simply because more men are getting tested, and not because the cancer has seen a sharp rise. With 49,029 confirmed cases, prostate tops the list of common cancers in England, followed by breast with 47,476 cases. Lung and bowel cancers are the next most commonly diagnosed. The head of the NHS, Simon Stevens, says that celebrity prostate cancer stories, like actor and comedian Stephen Fry’s, have helped raise awareness of the importance of having prostate cancer tests. Fry was diagnosed with prostate cancer in 2018, which he says was “thankfully caught in the nick of time". He subsequently underwent prostate cancer surgery. Prostate cancer has a high survival rate, with Cancer Research UK statistics showing that more than 8 in 10 (84%) men diagnosed with the disease in England and Wales survive for 10 years or more. But the key to successfully treating prostate cancer is to detect it early and begin treatment as soon as possible, which is why it’s crucial for men to get tested on a regular basis. Cancer tsar Prof Peter Johnson said: “As people live longer, we're likely to see prostate cancer diagnosed more often, and with well-known figures like Rod Stewart, Stephen Fry and Bill Turnbull all talking openly about their diagnosis, more people will be aware of the risk.”
Scientists from Cardiff University in the UK have discovered a part of our immune system that could be harnessed to kill all types of cancer. Despite their work being at an early stage, the team says the newly-discovered technique killed prostate, breast, lung and other cancers in lab tests. The findings of their research, which are published in the journal Nature Immunology, have not yet been tested in humans, but, nevertheless, the researchers say they hold “enormous potential.” The scientists made their potentially game-changing discovery while looking for “unconventional” ways the immune system naturally attacks tumours. They found a T-cell in blood that could find and kill a wide range of cancers, while leaving normal tissues untouched. Speaking about their findings, researcher Prof Andrew Sewell said: “It raises the prospect of a 'one-size-fits-all' cancer treatment, a single type of T-cell that could be capable of destroying many different types of cancers across the population.” While T-cell cancer therapies are nothing new, with treatments like CAR-T already being used to seek out and destroy cancer, the Cardiff researchers’ discovery is exciting because it could lead to treatments being developed that are more effective against solid cancers (those that form tumours). The researchers say their discovery has the potential to lead to a "universal" cancer treatment.
While it’s been known for quite some time that increased exposure to ultraviolet (UV) rays increases a person’s chances of developing skin cancer, no link has ever been found between precipitation and cancer risk, until now… A new study has revealed a potential link between living in cold, wet regions and increased cancer prevalence. The study, the results of which are published in the journal Environmental Engineering Science, is the first in the United States to check if a relationship exists between cancer rates, precipitation, and climate zone. To find out, the scientists collated data on breast cancer, colorectal cancer, lung cancer, ovarian cancer, and prostate cancer. They also used county-level data relating to cancer incidence, climate, and demographics. Having adjusted for age, gender, ethnicity, income level, population age, and diversity, the scientists identified a strong association between increased precipitation and an increase in incidence of all cancers. While it is important to note that not all cancer types were included in the analysis, the findings are still significant and strongly suggest climate zone is a risk factor for many cancers.
Researchers have found fat in overweight and obese people’s lungs. It’s the first time such a discovery has been made and could provide important clues as to why overweight and obese people have an increased risk of asthma. For the research, a team from Australia analysed lung samples from 52 deceased individuals. They found the amount of fat present increased in line with Body Mass Index (BMI). Being overweight/obese is already linked to having asthma, but it was previously thought that excess weight pressing on the lungs was the main reason for this. However, the Australian researchers say fatty tissue in the walls of airways takes up space and causes inflammation, which can lead to wheezing and asthma. Speaking about the findings of the research, which are published in the European Respiratory Journal, Dr Peter Noble from the University of Western Australia said: “We’ve found that excess fat accumulates in the airway walls where it takes up space and seems to increase inflammation within the lungs. “We think this is causing a thickening of the airways that limits the flow of air in and out of the lungs, and that could at least partly explain an increase in asthma symptoms.” Experts say that more research is now needed to find out whether the build-up of fatty tissue could be reversed through weight loss. In the meantime, asthma patients should be supported to achieve a healthy weight.
A new tumour-agnostic drug has been approved for use in Europe. The revolutionary drug, experts say, has the potential to cure more cancer patients and reduce side-effects. Called larotrectinib, the new drug does not care where the cancer is growing in the body and instead looks for a specific genetic abnormality, which means it can be used to treat a wide range of tumours. Doctors in the UK have said the new drug is “a really exciting thing” and marks a move away from having ‘drugs that treat breast cancer’, ‘drugs that treat bowel cancer’ and ‘drugs that treat lung cancer’, to having drugs that target the genetic make-up of each patient’s tumour. However, the decision by European regulators does not mean that any cancer patient can take advantage of larotrectinib right away. Its approval for use right now only applies to patients with solid tumours that have been caused by a genetic abnormality known as an NTRK gene fusion. This rare abnormality happens when part of an individual’s DNA accidentally merges with another, leading to an alteration in the body’s blueprint that allows cancer to grow. Speaking about the drug development, Dr Julia Chisholm, a children's cancer consultant at the Royal Marsden Hospital in London, said: “It is a really exciting thing, as is it works across a range of cancers. It's not confined to one.”
New research suggests that tickling the ear with a small electric current could help rebalance the body’s nervous system in people over-55 and help them age more healthily. The therapy works by stimulating the vagus nerve, the longest of the nerves that connect the brain with other parts of the body such as the heart, lungs and gut. The vagus nerve is usually difficult to access and usually requires surgical intervention so that electric stimuli can be delivered. However, one small branch of the vagus nerve reaches a part of the outer ear and that’s where the researchers from the Universities of Leeds and Glasgow — both in the United Kingdom – stimulated it from. Patients who received the electric stimuli for 15 minutes a day over a 14-day period noted improvements in body, sleep and mood. As we age, our body’s nervous system gradually becomes out of balance and the sympathetic branch begins to dominate. This makes us more prone to diseases, such as hypertension and heart problems, as well as anxiety and depression. The researchers found that the electric ear tickling therapy – named so because that’s how it feels – helped rebalance the body’s nervous system by increasing parasympathetic activity and decreasing sympathetic activity. People with the greatest imbalance at the start of the trial showed the biggest improvement at the end.
The humble garden snail could provide us with some ammunition in the fight against aggressive bacteria, according to two researchers from the United Kingdom. Intrigued how garden snails spend their lives sliding over dirt and coming into contact with deadly bacteria, yet don’t seem affected, Sarah Pitt, Ph.D. and Alan Gunn set out to discover why. It seems the answer lies in the mucus snails excrete. After analysing snail mucus, Pitt, principal lecturer in the School of Pharmacy and Biomolecular Science at the University of Brighton, and Gunn, subject lead for biosciences in the School of Natural Sciences and Psychology at Liverpool John Moores University, discovered four new previously unknown proteins. What’s more exciting is that two of these proteins appear to have strong antibacterial properties – especially against aggressive strains of Pseudomonas aeruginosa, a bacterium that causes dangerous lung infections in people who have cystic fibrosis. Speaking about the findings of their research, which appears in the British Journal of Biomedical Science, Pitt said: “In previous work, we found that the mucus consistently and convincingly inhibited the growth of one species of bacterium P. aeruginosa, a tough bacterium that can cause disease, but it did not seem to work against other bacteria. “So, in this study,we tried all the control strains of P. aeruginosa we had available in the lab here at the university as well as five strains taken from patients with [cystic fibrosis] who had lung infections with this bacterium.” The new discoveries could open up new possibilities in the fight against bacterial infections.
A US study suggests that Artificial Intelligence (AI) is better than specialist doctors at identifying lung cancer. It’s a finding that could revolutionize cancer screening in the future, potentially allowing tumors to be found at an earlier stage and improving treatment outcomes. According to the study - which was conducted by researchers from Northwestern University in Illinois and the Google Health Research Group – Artificial Intelligence was able to outperform six specialist cancer doctors when it came to identifying cancer from a single CT scan. When multiple CT scans were used, the AI and the doctors were equally effective. Prior to the tests, the AI was trained with 42,290 CT lung scans from nearly 15,000 patients. It was not told what to look for in a CT scan, merely which patients went on to develop cancer and which didn’t. The results of the study, published in Nature Medicine, show that AI can not only boost cancer detection by 5%, but can also reduce false-positives by 11%. Speaking about the findings of the research, Dr Mozziyar Etemadi, from Northwestern University, said: “Not only can we better diagnose someone with cancer, we can also say if someone doesn't have cancer, potentially saving them from an invasive, costly, and risky lung biopsy.”
A British teenager has become the first person in the world to have a drug-resistant bacterial infection treated by genetically engineered viruses. Isabelle Holdaway, 17, was given just a 1% chance of survival after a double lung transplant to treat her cystic fibrosis left her with an intractable bacterial infection that could not be treated with antibiotics. Her arms, legs and buttocks had numerous big, black, festering lesions where the bacteria were pushing up through her skin. She finally ended up in intensive care after her liver began to fail. Every previous patient in Isabelle’s situation died – some within a year, despite aggressive treatment. Desperate for a solution, Isabelle’s mother researched alternative treatments online and came across phage therapy. It’s not new; doctors have been using it for nearly a century, but its use has been eclipsed by antibiotics because they are much easier to use. Isabelle’s care team at Great Ormond Street Hospital contacted Prof Graham Hatfull at the Howard Hughes Medical Institute, in the US, who had the world's largest collection of phages (approximately 15,000). Hatfull and his team identified three potential phages that would be effective in tackling Isabelle’s bacterial infection and genetically modified two of them to make them more effective. Isabelle was injected with the cocktail of phages twice daily and they were also applied to the lesions on her skin. Within just six weeks, a liver scan showed that the infection had essentially disappeared. Phage therapy involves injecting bacteria-killing viruses into a patient’s body which track down, infect and ultimately kill bacteria. The phages hijack the bacterial cell and turn it into a phage factory until the viruses burst out of the bacteria killing it in the process. While Isabelle’s fatal infection has not been completely cured, it is under control and she is beginning to lead a normal life. She still has two infusions of phages every day and is currently waiting for a fourth phage to be added to the mix, which will hopefully clear the infection completely.
Nobody likes to see a baby with a cold. After all, runny noses and a cough are bad enough when you’re fully grown, let alone when you’re still just an infant. But new research suggests that babies who are born with lots of different bacteria in their noses are more likely to recover quicker from their first cold and could help bolster the way we deal with colds going forward. The findings of the research are interesting because the common cold is caused by a virus, yet it would appear that bacteria found in the respiratory tract do play a part when it comes to recovery. Indeed, the researchers from the University Children's Hospital of Basel found that babies who have lots of different bacteria living in their nose tend to recover more quickly from their first respiratory virus. Moreover, babies with fewer different types of bacteria take longer to recover. Prof Tobias Welte, President of the European Respiratory Society, said: “There is an association between respiratory symptoms in babies in the first year of life and the development of asthma by school age. “We do not yet fully understand this link but the bacteria living in the upper airways could play a role.” He also welcomed further research to help determine the relationship between bacteria, respiratory infections and long-term lung health.
By 2043, obesity will surpass smoking to be the biggest preventable cause of cancer in UK women. That’s one of the shocking new predictions to come out of a report by Cancer Research UK. At present, around 7% of cancers in women are linked to being overweight and obese, while 12% are said to be caused by smoking. But as the number of individuals who smoke continues to fall and obesity rates continue to rise, the UK cancer charity believes that gap will completely disappear over the next 25 years (assuming current trends continue). In fact, by 2035, the percentage of cancers caused by smoking and by carrying excess weight will almost be equal (25,000 cancer cases each year related to smoking vs. 23,000 related to being overweight). However, after just another eight years (by 2043), being overweight and obese is likely to be linked to even more cases of cancer in women than smoking. Interestingly, the cancer charity says that obesity will not overtake smoking as the leading cause of cancer in men until some time later. The reason for this, though, is simply because more men than women smoke. While obesity is more prevalent among men too, it is thought to be a greater catalyst in women for developing cancer. Professor Linda Bauld, Cancer Research UK's prevention expert, said the UK government must act now to stem the tide of obesity-related cancers. “That's why we are raising awareness of the link between cancer and obesity and calling for measures to protect children, like a ban on junk food adverts before 9pm and for restrictions on price promotions of 'less healthy' products,” she said. Smoking-related cancers include: acute myeloid leukaemia lung bladder bowel cervical pancreatic stomach Obesity-related cancers include: bowel gall bladder kidney liver breast ovarian thyroid
One in five men and one in six women will develop cancer in their lifetime. That’s one of the stark predictions revealed in a new report from the WHO’s International Agency for Research on Cancer (IARC), which is based in Lyon, France. This year alone, there will be 18.1 million new cases of cancer and 9.6 million people will die with the disease worldwide. This represents a significant increase from 14.1 million cases and 8.2 million deaths in 2012. The report also predicts that by the end of the century, cancer will be the number one killer globally and the single biggest barrier to people living long lives. Looking closely at data from 185 countries, the researchers focussed on 36 different types of cancer. Lung cancer, colorectal (bowel) cancer and female breast cancer are thought to be responsible for a third of all cancer cases worldwide. Researchers have attributed the rise to the world’s growing and ageing population. That’s because more people equals more cancer, and as people get older their cancer risks grow. Moreover, as countries become wealthier, more of the people living in them develop lifestyle-related cancers. Speaking about the report, Dr. Christopher Wild, director of the International Agency for Research on Cancer, said: “These new figures highlight that much remains to be done to address the alarming rise in the cancer burden globally and that prevention has a key role to play.” “Efficient prevention and early detection policies must be implemented urgently to complement treatments in order to control this devastating disease across the world.”
New figures show that rates of tuberculosis (TB) in England are at their lowest level in 35 years, having fallen by a third in the last six years. According to data from Public Health England, tuberculosis rates have declined by 38% since 2012. In fact, there was a 9.3% decline in 2017 alone, highlighting how the country’s efforts to eradicate the disease are proving effective. Improved diagnosis, treatment and awareness are being credited for the decline. However, despite the fall, England still has one of the highest rates of TB in Western Europe, with 5,200 people affected in 2017. Dr Sarah Anderson, head of the National TB Office at Public Health England, said: "People often think that TB is a Victorian disease that is no longer a problem in England, but in fact it still affects over 5,000 people a year and there is still a lot to do until the target to eliminate TB is met.” TB is a bacterial infection that primarily affects a person’s lungs and it is spread through coughs and sneezes. But despite its infectious nature, it is actually quite difficult to catch. Nevertheless, it can be fatal if left untreated. Another issue is that TB is becoming resistant to some of the major drugs used to treat it, which is why the BCG vaccine that offers protection against TB is recommended for babies, children and adults alike who are at risk of catching the disease.
Using cleaning products regularly can be as bad for your lungs as smoking 20 cigarettes a day, a new study has found. Tracking people with an average age of 34 over a 20-year period, scientists at Norway’s University of Bergen found that women who regularly used cleaning products had lung function decline equivalent to those who smoked 20 cigarettes a day. For the study, the researchers measured the lung function of participants by testing the amount of air they were able to forcibly breathe out. They then examined the results alongside surveys answered by the study participants. They found that women who regularly used cleaning products had noticeably decreased lung capacities, as well as increased rates of asthma. Prof Cecile Svanes, who led the team from Bergen, said: "We feared that such chemicals, by steadily causing a little damage to the airways day after day, year after year, might accelerate the rate of lung function decline that occurs with age". So what should you be using instead of cleaning products? According to the scientists, microfiber cloths and water should be “enough for most purposes”, while keeping your home ventilated and using liquid cleaners, not sprays, could also help lessen the impact of cleaning products.
New figures show that for the first time ever the number of men dying from prostate cancer in the UK has overtaken female deaths from breast cancer. While lung and bowel cancer remain the top cancer killers, prostate cancer is now third, according to figures released by Prostate Cancer UK. In 2015, 11,819 men died from prostate cancer, compared to 11,442 women from breast cancer – a reality that Prostate Cancer UK says is due to advances in diagnosis and treatment of breast cancer. The charity says that the UK’s aging population is one of the reasons why more men are developing and dying from prostate cancer. Angela Culhane, chief executive of Prostate Cancer UK, said prostate cancer survival rates could be increased by developing better diagnostic tests and using them to form a nationwide screening programme. At present, there is no single, reliable test for prostate cancer. Also, men with the disease can live for decades without showing any symptoms. Those most at risk are men with male relatives who have had the disease, black men and men aged over 50. Ms Culhane said: “It's incredibly encouraging to see the tremendous progress that has been made in breast cancer over recent years. “The good news is that many of these developments could be applied to prostate cancer and we're confident that with the right funding, we can dramatically reduce deaths within the next decade.” You can find out more about prostate cancer treatment with us here at France Surgery by visiting the oncology section of our website and selecting the prostate cancer link.
Developing a universal blood test for cancer has been one of the biggest goals in medicine ever and now scientists at John Hopkins University have taken a huge step towards achieving it. The team have trialled a test that can detect eight common forms of cancer, with the ultimate goal being to develop an annual test that can catch cancers early and save lives. While more work is needed, experts in the UK have described the breakthrough as “enormously exciting”. The test works by picking up on tiny traces of mutated DNA and proteins released into a person’s bloodstream by tumours. The CancerSEEK test, as it is known, looks for mutations in 16 genes and eight different proteins released by tumours. In a trial involving 1,005 patients with cancers in the stomach, liver, ovary, pancreas, colon, oesophagus, lung or breast, which had not yet spread to other tissues, the test was able to successfully detect 70% of the cancers. The test is particularly exciting as it was able to detect some cancers that currently have no early detection screening programmes. Pancreatic cancer is one area where the test could really make a big difference. At present, four in five pancreatic cancer patients die within the year they are diagnosed. That’s because the disease emits so few symptoms and sufferers are often diagnosed too late. The CancerSEEK test will now be trialled on individuals who have not been diagnosed with cancer. This will be the real measure of its effectiveness and usefulness.
Researchers at an Oxford hospital have developed an Artificial Intelligence (AI) system that can accurately diagnose heart and lung scans. The new AI could lead to more people being diagnosed earlier and prevent patients being sent home when they are still at risk of having a heart attack. It’s though the system will save the NHS billions of pounds by enabling various diseases to be detected much earlier. The heart disease technology will be available to NHS hospitals for free this summer. Currently, cardiologists use a person’s heartbeat to tell if there is a problem. However, even the most experienced doctors get it wrong in one in five cases. This leads to a patient being sent home when they are still at risk of a heart attack or undergoing an unnecessary operation. The AI system can pick up details on the scans that doctors cannot see, resulting in a more accurate diagnosis. So far, the system has been tested in clinical trials and the results aren’t expected to appear in a peer-reviewed journal until later this year. However, one of the system’s developers has said the data shows it greatly outperformed his fellow specialists. The government's healthcare tsar, Sir John Bell, has indicated that AI could "save the NHS". "There is about £2.2bn spent on pathology services in the NHS. You may be able to reduce that by 50%. AI may be the thing that saves the NHS," he said.
A new large-scale study has found that using aspirin long-term could slash the chances of developing gastrointestinal cancer. Of all the gastrointestinal cancers, which include pancreatic cancer, liver cancer, oesophageal cancer, stomach (or gastric) cancer and small intestine cancer, colorectal cancer is the most common in the western world. While there are a number of lifestyle changes people can make to reduce their risk of developing cancer, including avoiding tobacco, limiting their alcohol consumption, eating healthier and exercising more, an increasing number of studies suggest the use of aspiring could also help. For this latest study, Prof. Kelvin Tsoi, of the Chinese University of Hong Kong, and his team set out to investigate the effect of aspirin use on gastrointestinal cancers. Over a 10-year period, the team of scientists examined over 600,000 participants and analysed how aspirin use affected their chances of developing gastrointestinal cancer. They found that aspirin users were 47% less likely to have liver and oesophageal cancer, 38% less likely to have stomach cancer, 34% less likely to have pancreatic cancer and 24% less likely to have colorectal cancer. In addition, aspirin use also significantly reduced the risk of leukaemia, lung cancer and prostate cancer.
A girl from the UK, who unfortunately died from a brain aneurism, has helped a record eight people, including five other children, through organ donation. Jemima Layzell, from the southwest of England, who died in 2012, donated her heart, pancreas, lungs, kidneys, small bowel and liver. Her parents said Jemima was a very clever, compassionate and creative girl, who would have been “very proud of her legacy”. According to NHS Blood and Transplant, no other donor has ever helped so many people. Normally, an organ donation results in, on average, 2.6 transplants – a fact that highlights just how unusual Jemima’s situation is. Her heart, small bowel and pancreas were transplanted into three different people. Two people received her kidneys, while her liver was split and transplanted into a further two people. Both of her lungs were transplanted into another patient. NHS Blood and Transplant said that too many people die unnecessarily while awaiting a transplant because too many parents do not agree to donate their children’s organs. Last year, 457 people died waiting for a transplant, including 14 children. At present, there are 6,414 people on the transplant waiting list in the UK, including 176 children. Jemima’s story will hopefully encourage more people to become organ donors and help save lives after they die.
We recently informed you about how researchers from Cambridge University believe a chemical compound found in dogfish sharks could be used to potentially halt the onset of Parkinson's Disease (here). Now scientists in Australia hope a drug that mimics part of a shark's immune system could be used to help treat an incurable lung disease in humans. People with idiopathic pulmonary fibrosis (IPF) - a condition that scars lung tissue - find that their breathing becomes progressively harder and they develop a persistent dry cough. At present, there is no cure for IPF, so treatment focuses on symptom relief and slowing the progression of the disease. Initial tests with the drug, AD-114, showed that it can successfully kill the cells that cause fibrosis. Researchers hope that human trials with AD-114 can commence as early as next year. Dr Mick Foley, from the La Trobe Institute for Molecular Science, was keen to stress that no sharks were harmed during the research, and just a single blood sample was taken from a wobbegong shark at Melbourne Aquarium for the tests. "It would be very nice to say one day that 'this person is alive because of what the sharks told us,'" Dr Foley said. IPF is a disease that kills more than 5,000 people in the UK alone every year, according to the British Lung Foundation.
France is world-renowned for its excellent healthcare facilities, and that's why so many people each year take the decision to come here and undergo a medical procedure with our help. But did you know that a team of French cancer researchers was one of the first in the world to develop a blood test that can detect lung cancer? Lead by Prof. Paul Hofman from Nice University Hospital and the Inserm research centre at Nice Sophia-Antipolis university, the simple test developed by the team can highlight circulating tumour cells years before any signs of a tumour appear. The team of French researchers conducted tests on a total of 245 cancer-free patients. Of these patients, 168 were heavy smokers with Chronic Obstructive Pulmonary Disease (COPD) - a risk factor for lung cancer - and 77 without COPD (42 smokers and 35 non-smokers). Circulating tumour cells were discovered in five of the 168 patients with COPD, all of who subsequently developed cancer. Fortunately, swift surgery to remove the cancer was successful and follow-up CT-scans a year later showed them to be in remission. Prof. Hofman said that the blood test allowed them to gain about four years on the cancer, which significantly increased the patients' chances of a positive outcome. The results of the "world first" tests were first published in late 2014 in the US open access peer-reviewed scientific journal Plos One.
A new study has found that a catheter placed in the vein under the collarbone appears to lower the risk of infections and clots in an intensive care unit patient’s bloodstream. In fact, according to the researchers behind the study, it lowered those risks by two to three times in comparison to catheters placed in other areas, such as the large vein in the groin or the jugular vein in the neck. Catheter-related infections usually occur as a result of bacteria on the skin which attach themselves to it as it’s inserted and find their way into the patient’s bloodstream. Despite placing a catheter in the vein under the collarbone being the preferred method, according to the study, a lot depends on the skill of the individual placing it. Ultrasound is inevitably used to guide the procedure and this reduces the risk of a patient encountering a problem like a collapsed lung. Lead researcher Dr. Jean-Jacques Parienti, from the department of biostatistics and clinical research at the Cote de Nacre University Hospital in Caen, France, said: "The [under the collarbone] route is the safest for the patient, provided that everything is done to reduce the risk of mechanical complications during insertion." The findings of the study were published in the New England Journal of Medicine on September 24. Photo via: National Cancer Institute
A study of 582 people, conducted in Europe and the US, has found that Nivolumab leaves cancer cells open to attack from the body’s immune system by preventing them from being able to hide. Lung cancer kills almost 1.6 million people worldwide every year and is particularly difficult to treat as it is usually diagnosed late and sufferers often have other smoking-related diseases which make them unsuitable for surgery. The trial involved patients who had advanced lung cancer and had already tried other treatments. Individuals who were on standard therapy at this stage lived for another 9.4 months, but those being treated with Nivolumab lived for an average of 12.2 months. However, patients whose tumours were producing high levels of PD-L1 – a protein that inhibits the body’s natural defences – lived for another 19.4 months after taking Nivolumab. The study’s lead researcher, Dr Luis Paz-Ares from the Hospital Universitario Doce de Octubre in Madrid, Spain, said: "[The results] mark a milestone in the development of new treatment options for lung cancer." The data was presented by pharmaceutical company Bristol-Myers Squibb to the American Society of Clinical Oncology and the findings were described as "giving real hope to patients". Cancer Research UK welcomed the results of the study and said that harnessing the power of the body’s immune system would be an "essential part" of cancer treatment. Photo credit: Phys.org
Doctors say that a “ground-breaking” cystic fibrosis therapy could dramatically improve the quality of life for sufferers of the condition. Patients usually die before they reach the age of 40 as they’re left prone to infection from the mucus that clogs and damages their lungs. But now, a major clinical trial on some 1,108 patients, the results of which were published in the New England Journal of Medicine, revealed that a combination of drugs had the ability to bypass the genetic errors that caused the condition and increase life expectancy as a result. In the UK alone, one in every 2,500 babies are born with cystic fibrosis and the Cystic Fibrosis Trust believes the new findings could “improve the lives of many”. A genetic condition, the DNA of cystic fibrosis sufferers contains an error which means the individual is unable to control salt and water levels in their lungs. A thick mucus forms and inexorably damages the lungs. Antibiotics have been used historically to prevent infection, but nothing has been developed to address the underlying problem for most sufferers. Lumacaftor and ivacaftor are the two drugs which when combined, improved the lung function of those patients that received them over the course of a 24-week trial. It was also reported that patients gained weight during the trial, something which was attributed to the mucus lining in the gut being affected too. Professor Stuart Elborn, who headed up the Queen’s University, Belfast part of the trial, said: “It is not a cure, but it is as remarkable and effective a drug as I have seen in my lifetime.” Photo credits: Discover magazine, The New York Time Magazine
The World Health Organisation (WHO) has recently announced that smart syringes that break after a single use should be being used for injections worldwide by 2020. It’s thought that reusing syringes contributes to over two million people annually being infected with diseases like HIV and hepatitis every year. Despite being more expensive, the WHO has said that the extra cost is still lower than treating the diseases. And with more than 16 billion injections being administered annually, plus the fact that normal syringes can be used over and over again, the switch to smart syringes is a significant step in the right direction. The smart syringes work by either retracting the needle or preventing the plunger from being pulled back after use. The Director of the WHO HIV/AIDS Department, Dr Gottfried Hirnschall, said: “Adoption of safety-engineered syringes is absolutely critical to protecting people worldwide from becoming infected with HIV, hepatitis and other diseases. This should be an urgent priority for all countries.” However, the switch to smart syringes won’t be easy and will need the backing of all stakeholders to ensure that supply meets demand during the crucial switchover phase. More information about the smart syringe announcement can be found in the full WHO press release.
Clinique des Cèdres, Toulouse Clinique des Cèdres was created in 1966 thanks to Dr Anduze-Acher. Since then it became the biggest private hospital in France with 603 beds and places. In 2003, its acquisition by Capio group – already settled in Toulouse with Polyclinique du Parc, Clinique St Jean du Languedoc, Clinique de Beaupuy – helped its development. Clinique des Cèdres provides state-of-the Art equipment to its medical teams. Amongst the mini invasive surgical techniques: Robotic: In urology for the prostate cancer treatment, the kidney and bladder surgery In gynaecology for the uterus cancer surgery and the pelvic node dissection In ENT for the oral cavity, pharynx surgery, for the cellulo-node, nasopharyngeal surgery (cavum) Coelio-surgery for bariatric surgery Computer-aided surgery and strereotactic for the treatment of brain tumors Mini-invasive surgery for spine surgery (disc prothesis), orthopaedic surgery (perecutaneous foot surgery & trauma surgery) and rectal surgery (haemorrhoidal Doppler-assisted dearterization) 2. Advanced diagnosis techniques: Fluorescence technique in endoscopy for the early detection of lung cancers and bladder tumors 3D plan sensor in cardiology for the diagnosis and treatment of heart attacks and thoracic pains and in neuro radiology for the brain exploration and the therapeutic treatment of some brain vascular anomalies Non invasive Diagnosis-Imaging system: 64 strips scan Computerised diagnosis, evaluation, and follow-up care for knee cruciate ligament UNITS: 1. SURGICAL UNITS: more than 20 theatres covering a extremely wide variety of surgeries: Digestive surgery: ceolioscopy - endoscopy Orthopaedic surgery: arthroscopy Neurosurgery: neuronavigation device (O-arm concept) Ophthalmology ENT Outstanding surgical equipments include a stereotactic frame, a laminar flow, a laser, electronic microscopes and a DaVinci robot. 2. RECOVERY UNITS: the rooms are equipped with modern monitoring equipments and are under permanent anaesthetis supervision. Specialized nurses have the responsability of the post-operation personal follow-up care of the patient. 3. DIAGNOSIS AND MEDICAL IMAGING DEPARTMENT Angiography - Coronarography - Echigraphy - MRI - Mammography - Conventional and interventional radiology - Scan 4. NUCLEAR MEDICINE Functional and metabolic medical imagining, not accessible with conventional imaging equipment is performed in this department. 5. MEDICINE 6. INTENSIVE-CARE AND CONTINUOUS MONITORING UNIT 7. EMERGENCIES 8. HELIPAD 9. FUNCTIONAL PHYSIOTHERAPY 10. PSYCHIATRY 11. ONE-DAY HOSPITALISATION
DESTINAZIONE FRANCE La francia ha attratto 83 milioni di turisti nell'anno 2012, questo la rende la destinazione più popolare al mondo. Nel paese ci sono 37 siti classificati come patrimonio mondiale dall'Unesco, oltre alle sue città di grande interese culturale, Parigi in primis, ma anche Tolosa, Strasburgo, Bordeaux, Lione ... Potrete trovare alcune tra le spiagge più belle, stazioni sciistiche e regioni di campagna molto diverse apprezzate soprattutto per la loro tranquillità e bellezza (turismo ambientale). Alcuni piccoli paesi pittoreschi sono stati classificati e promossi dall'associazione les Plus beaux villages de France. E' stata creata anche una classificazione per proteggere più di duecento tra giardini e parchi presenti sul territorioselezionati dal ministero della Cultura Francese. Non potrete mai dimenticare alcuni luoghi, le atmosfere e i paesaggi. Questo è il caso, per esempio, di Tolosa, Rocamadour, Conques e del Cirque de Gavarnie, posti magici perfetti per una visita di un giorno o per un lungo soggiorno. La regione dei Midi-Pyrénées conta circa 25 destinazioni turistiche indimenticabili che permettono di scoprire non soltanto la storia e la bellezza della regione, ma anche l'innato senso di ospitalità della sua gente. La “Festa della Musica” Completamente diversa da un festival musicale, la festa della musica è prima di tutto una festa popolare, aperta a tutti i partecipanti: musicisti professionisti, dilettanti e amatori. Questa giornata della musica è aperta a tutte le espressioni e gli stili musicali in un atmosfera di festa. E' destinata ad un grande pubblico per diffondere le composizioni musicali sia per i giovani che per i meno giovani di qualsiasi estrazione sociale. Queste caratteristiche creano l'occasione di condividere un momento molto particolare attraverso la musica. Tutte le cliniche e gli ospedali selezionati sono situati vicino ad aereporti internazionali e città che offrono differenti attrazioni di interesse culturale e turistico per permettere ai pazienti in convalescenza o alle loro famiglie e amici di scoprire nuovi orizzonti.