French schools have closed for at least three weeks under a third national lockdown to fight rising Covid-19 cases. French President Emmanuel Macron announced last week that schools would switch to remote learning from the beginning of this week. Other lockdown measures, introduced in some parts of France earlier this month, including Paris, have also been extended to other areas. From last Saturday, all non-essential shops closed and there is now a ban on travelling more than 10km (6 miles) from home without good reason. Last Wednesday, the country's health ministry reported 59,038 new cases. France has so far reported more than 4.6 million cases of coronavirus and 95,495 Covid-related deaths. In a live televised address, Mr Macron described the situation in France as "delicate". He added that April would be a “crucial” month in the battle against Covid-19. "We will lose control if we do not move now," he said. Mr Macron outlined that the race to vaccinate would continue alongside attempting to control the spread of the virus. He said that while schools would be closing from this week, classes would remain open for the children of key workers. Image: French President Emmanuel Macron, courtesy of Foundations World Economic Forum, licensed under the Creative Commons Attribution 2.0 Generic license.
In an effort to ramp up its vaccination drive, France has confirmed it will open at least 35 giant ‘megacentre vaccinodromes’ across the country by April. Health Minister Olivier Véran this week confirmed: “The health service and the army will work to develop a certain number of giant vaccination centres - we might call them ‘vaccinodromes’ or ‘megacentres’, whatever name you want to use.” Mr Véran stated his goal of having “10 million people vaccinated with at least one dose by mid-April”, with the campaign rollout set to speed up next month “because supplies of the vaccine will rise”. France’s total population is c. 67 million. From Marseille to Toulon to Lyon and Paris, work is ongoing to turn some of the nation’s largest sporting arenas, including Paris’s Stade de France, into mass Covid-19 vaccination centres. However, the health minister has said that his long-term goal is to have “one or two megacenters per department”, which equates to “100 to 200” across the entire country. Once opened, the vaccinodromes will aim to give 1,000 to 2,000 vaccines per day. At present, the average number of doses given at vaccination centres is around 500 per week. Image: Stade de France, courtesy of Zakarie Faibis, licensed under the Creative Commons Attribution-Share Alike 4.0 International license.
Musicians in Montauban, a commune in the Tarn-et-Garonne department in the Occitanie region in southern France, performed a public concert last weekend for the first time in months. But don’t worry, no Covid-19 restrictions were broken because the musicians performed from open windows in the centre of the town. The Fenêtres musicales (Musical windows) event took place on Sunday, March 21. Musicians across the town opened windows in central buildings, and played their instruments for passing members of the public. Hugo Schmitt, saxophonist at the Orchestre de la Cité at Ingres, told FranceInfo: “After a year without any concerts, it’s a real relief. To be able to play in the centre of Montauban, in beautiful apartments next to open windows, especially during this period, which has been hard for us as artists, it’s really a gift.” Around 20 musicians played via open windows for the event, with the “concert” lasting around 90 minutes. A small crowd also gathered to listen to three singers and a pianist lay a rendition of Mozart’s Nocturnes. One of the singers, Eugenie Berrocq, said: “Because we can’t go to theatres, and we can’t do this in a more conventional or traditional way, we have to reinvent ourselves. There are many artists who have done this, and I think it’s a very good idea to do it in this way.” One Montauban resident said: “We’ve been without culture for a year now, it’s starting to get a bit long. So this kind of initiative is great.” Another said: “It’s nice, it does you good to watch people playing. We’ve missed it a bit.” *Image courtesy of FranceInfo
The French Government has confirmed a three-step plan to open restaurants, although no firm date has been set for when it will begin. Following a meeting between hospitality representatives and government ministers on March 16, Didier Chenet, president of hospitality union GNI, told news source FranceInfo the date for reopening was dependent on two factors: “The daily number of Covid cases and the number of people vaccinated”. Since the second national lockdown was imposed more than four months ago on October 29, 2020, restaurants and cafes have been closed in France. The government’s initial plan was to reopen such establishment on January 20, 2021, but this was delayed indefinitely as daily Covid-19 cases remained high and health experts feared a spike could occur as a result of Christmas and New Year celebrations. The three-stage plan, Mr Chenet said, would begin with the opening of hotels for breakfast and dinner. Next would be terraces and interiors in cafes and restaurants, including hotel restaurants, with a 50% capacity limit. Finally, “In the third phase establishments would be fully open, with health protocols in place,” he said. Mr Chenet also revealed that each phase would last four weeks.
Germany, France, Italy and Spain have joined the list of countries to suspend use of AstraZeneca’s COVID-19 vaccine. The countries took the decision after reports have arisen of dangerous blood clots in some recipients. Meanwhile, AstraZeneca and European regulators have said there is no evidence the vaccine is to blame. The AstraZeneca shot is one of three vaccines currently in use in Europe. Nevertheless, the blood clot concerns and subsequent cessation of its use represents another setback for the EU’s vaccination drive – which has already been slow off the mark compared to similar campaigns in the United Kingdom and the United States. The EU’s drug regulatory agency has called a meeting for this week to review experts’ findings on the AstraZeneca vaccine and decide how to proceed. All this comes as much of Europe tightens restrictions on schools and businesses as Covid-19 cases surge. In Germany, the decision to halt the use of the Astrazeneca vaccine was taken following advice from the country’s vaccine regulator, the Paul Ehrlich Institute. It called for further investigation after blood clots were found in the brains of seven people who had been vaccinated. In response to the situation, Astrazeneca published a press release offering ‘reassurance on the safety of its COVID-19 vaccine based on clear scientific evidence’.
France is working on a digital health pass to allow people to resume leisure activities and travel, a French Government spokesperson said on Wednesday. Speaking after a recent cabinet meeting, Gabriel Attal told reporters that the digital health passes would allow people to resume certain leisure activities in France, such as going to museums, restaurants, sports centres and travelling overseas, in the coming months. The idea is also being considered at a European level to facilitate travel between different countries in Europe and possibly beyond. Last month, French President Emmanuel Macron said introducing vaccine passports would be unfair because they would discriminate against certain groups, such as the young, in particular, who aren’t eligible to be vaccinated yet. However, Macron said he is in favor of a “health pass” that would also include whether a person has antibodies from getting COVID-19 or the results of a negative test, and could be used to get access to restaurants or other venues. [Related reading: France eyes easing of COVID-19 restrictions from next month]
France is gearing up for a possible easing of COVID-19 lockdown restrictions from mid-April, as vaccines, to date, are proving effective at lowering infection rates. French government spokesman Gabriel Attal said on Wednesday that while the nation is still facing hard times, “For the first time in months, the return to more normal living conditions is in sight.” Attal said vaccinated groups (mainly the elderly) are witnessing falling infection rates, which, he said, is a sign that the country’s vaccination program is working and should be sped up. "It is neither a distant nor uncertain horizon - it is an horizon that is getting closer and closer. We hope maybe from mid-April, and we are preparing for it. "The president (Emmanuel Macron) asked us to submit proposals that could allow for a cautious re-opening of the country soon,” he said. Attal added that the goal of vaccinating the most fragile was to reduce hospitalizations and safeguard the nation’s health care system, which is key to easing restrictions. Earlier this week, Health Minister Olivier Veran said France will retain its current measures aimed at limiting the spread of COVID-19, including a nighttime curfew, as a bare minimum for the next four to six weeks. Other measures now in force include the closure of bars, restaurants, museums, sports and music venues. COVID-19 is the disease caused by the coronavirus.
People in France aged over 65 with existing health problems will be allowed to be given the AstraZeneca COVID-19 vaccine, after the French Government reversed its policy. When the AstraZeneca vaccine was approved for use by European Union regulators, the French Government said it should only be given to eligible people under 65 because data from trials in older age groups was limited. The AstraZeneca vaccine will now be offered to people up to the age of 74. However, the shot has been hit by a slow rollout and a lack of trust. French Health Minister Olivier Veran said Monday: "Anybody aged 50 or over who is affected by co-morbidities can get the AstraZeneca vaccine, including those between 65 and 74." The announcement has the potential to affect more than two million people. British health authorities released new data on Monday that showed the AstraZeneca vaccine reduced hospitalization from COVID-19 by more than 80%. The vaccine is widely used in the UK but has missed delivery targets in the EU. People aged 75 and over would continue to get the Pfizer and Moderna vaccines only, Veran said. Meanwhile, Germany still hasn’t cleared the AstraZeneca vaccine for over 65s. This has led to fewer people stepping up for the shot and several doses being wasted. Image courtesy of Marco Verch on Flickr, licensed under the Creative Commons Attribution 2.0 Generic (CC BY 2.0)
A baby has been born in France following a uterus transplant for the first time, the hospital treating the mother and baby announced on Wednesday. While such births are not unprecedented, they are extremely rare, happening after a woman whose own uterus is damaged or missing has had a cutting-edge procedure to have a healthy one transplanted. The baby, a girl weighing 1.845kg, was born last Friday, according to the team at the Foch Hospital outside Paris. "Mother and baby are doing well," said Dr Jean-Marc Ayoubi, head of gynaecology, obstetrics and reproductive medicine at the hospital. The 36-year-old mother, who reports are naming only as ‘Deborah’, was born without a uterus because of a rare condition known as Rokitansky Syndrome, which affects about one in 4,500 women. Deborah received a uterus transplant in March 2019 from her own mother, then aged 57. The transplant was performed by the same team at the Foch Hospital that delivered the new baby. The first ever birth after a uterus transplant was in Sweden in 2014 and there have been other such births in the United States and Brazil to date. However, they remain rare. Nevertheless, this new birth, as well as those before it, will give hope to women who suffer similar reproductive problems that they maybe have alternatives to adoption or surrogacy.
Europe's oldest living person has survived COVID-19 after testing positive just weeks before her 117th birthday. Sister André, a French nun who was born in 1904, tested positive in the retirement home where she lives in Toulon, southern France, on January 16, according to the home’s communications director, David Tavella. André, who was born Lucille Randon, showed no symptoms from the virus and didn’t even know she was infected until she received her positive test. Despite no visitors being allowed because of strict COVID protocols, André is preparing to celebrate her 117th birthday today, Thursday 11th February. She will reportedly receive video messages from her family and the local mayor, as well as taking part in a video Mass, Tavella said. André's birthday meal will feature her favorites: foie gras, baked Alaska and a glass of red wine, Tavella added. Remarkably, André has lived through two world wars, as well as the 1918 Spanish Flu pandemic that infected around 500 million people. While Andre is the oldest living person in France today, she’s not the oldest in the world. That crown is held by Kane Tanaka, a Japanese woman who was born in 1903, according to the Gerontology Research Group (GRG). * Image credit Gérard Julien/AFP/Getty Images
Last Saturday, February 6, France reported both a fall in new COVID-19 infections and in the number of patients being treated in hospital. The country registered 20,586 new confirmed COVID-19 cases, down from 22,139 the previous day and marking the third straight daily fall. Meanwhile, hospitals across the country were treating 27,369 people for the disease, down 245 from the previous day, marking the fourth consecutive daily fall. The fall in numbers comes as France continues with its COVID-19 vaccination programme, with 1.86 million people now having received their first dose. Almost a quarter of a million people (247,260) have also received their second dose. At present, France has three vaccines approved for use: Pfizer/BioNTech, Moderna and AstraZeneca, the latest to be received. The country has taken delivery of 273,600 AstraZeneca, according to the health ministry, with a second batch of 304,800 doses scheduled to be delivered this week. The initial AstraZeneca shots were prioritized for health personnel under 65, with the first injections taking place over the weekend. While the arrival of the AstraZeneca shot will help France accelerate its vaccination programme, the quantities that are expected to be delivered are likely to be less than first thought. Nevertheless, with a third approved vaccine and COVID numbers falling, pressure on the French health system is easing day by day.
Against expectations, France has resisted imposing a nationwide lockdown, choosing to introduce new Covid-19 border restrictions instead. Under the new restrictions, all non-essential travel from outside the EU has been banned and testing requirements for travellers from within the EU have been tightened. French Prime Minister Jean Castex said France's night curfew would also be more tightly enforced and large shopping centres would close. It had been expected that French President Emmanuel Macron would impose a third national lockdown to contain Covid-19. However, the French premiere opted to tighten existing restrictions on travel and shopping instead. The move sees France following a different path than its two biggest neighbours Britain and Germany, at a time when the more contagious UK variant of the disease is spreading rapidly across Europe. [Related reading: Moderna says its vaccine will work against new COVID variants] "Everything suggests that a new wave could occur because of the variant, but perhaps we can avoid it thanks to the measures that we decided early and that the French people are respecting," Health Minister Olivier Veran told the Journal du Dimanche (JDD) newspaper on Sunday. Despite the news of tighter border restrictions, France Surgery’s proprietary telehealth platforms remain open and accessible to all of our international clients, one of the main benefits of remote healthcare.
Despite Covid-19-related lockdowns continuing in many countries across the world, the Michelin Guide has awarded its coveted stars for 2021 — and France (including Monaco) now has more three-star establishments than any other country. Originally due to be announced at a lavish gala ceremony in Cognac, southwest France, the Michelin awards were broadcast via Facebook on Monday from the Jules Vernes restaurant (one star) on the second floor of the Eiffel Tower in Paris. Social distancing rules forced Michelin to call off the event in Cognac, which would have been the first time the awards were held outside Paris. Ahead of this year’s awards, Michelin had promised that no three-star restaurants would be demoted as the global pandemic continues, causing many establishments to remain closed or switch to take-aways and deliveries. One of the main talking points of this year’s awards was ONA, which stands for Origine Non Animale or Non-Animal Origin. The vegan restaurant in Ares near Bordeaux, which serves only plant-based foods, became the first of its kind in the country to be awarded a Michelin star. Vegan restaurants in the US, Germany and Spain have already received Michelin stars in recent years. ONA was also awarded a green star for its strong ethical and sustainable practices.
More than 40 countries have banned individuals arriving from the United Kingdom due to concerns about a new variant of coronavirus. France shut its border with the UK for 48 hours, which meant no lorries or ferries could leave from Dover. Meanwhile, flights from the UK have either been suspended or are in the process of being suspended to countries across the world, including Belgium, Canada, Germany, Hong Kong, India, Ireland, Italy, Portugal, Romania, Russia, Spain and Switzerland. The UK’s postal service, Royal Mail, has also temporarily suspended all services to mainland Europe, due to the "current restrictions around air, road, ferry and train movements from the UK". UK Prime Minister Boris Johnson said he spoke with French President Emmanuel Macron about the situation, saying that both sides wanted to resolve "these problems as fast as possible". The ban on UK arrivals came about after a new strain of coronavirus – which is reportedly 70% more transmissible – has been spreading across London and south-east England. However, health officials have said there is no evidence that this new variant is more deadly or would react differently to vaccines. French Europe Minister Clément Beaune is expected to announce today what measures were being introduced "after this phase of emergency and harsh precaution that we had to take". Any measures, he said, would come into effect from Wednesday. [Related reading: France lifts lockdown, opens borders for Covid-safe countries]
After about a month and a half of complete lockdown, France’s Covid-19 restrictions are easing. While several types of venue will remain closed, the lockdown will be replaced with a nightly curfew, designed to avoid another spike of cases. French Prime Minister, Jean Castex, said that the health situation in France has improved considerably in recent weeks. However, he warned that the second wave of the pandemic had yet to end. “We have not yet reached the end of this 2nd wave, and we will not be, on December 15,” he said, explaining why a nightly curfew would be in place, and some venues prevented from reopening. In addition to the lockdown ending, France has also opened both international travel and travel to different regions of the country for non-essential reasons. This will allow tourists and second homeowners to once again visit France, as well as enabling people to travel to see relatives and friends in other parts of the country or other countries. In his speech announcing the new measures, PM Castex said that travel on the evening of December 24 will be allowed, but not for more than six adults at a time. He also reminded French citizens to respect the hygiene and social distancing guidelines. Under the new measures, travel between France and the following countries/territories is now permitted: - European Union - Andorra - Australia - The Holy See - Iceland - Japan - Liechtenstein - Monaco - New Zealand - Norway - Rwanda - San Marino - South Korea - Singapore - Switzerland - Thailand - United Kingdom
Telehealth solutions have come into their own during the ongoing Covid-19 pandemic. Indeed, adoption of telehealth services has increased by more than 2,000% since last year. With both physicians and patients alike reaping benefits from telehealth solutions, it’s inevitable that some ambulatory care and services will never return to being face-to-face. However, as solutions mature and become more readily adopted, healthcare providers need to realize that a one-size-fits-all approach to telehealth will not afford the best outcomes for patients. Before implementing any telehealth services at all, healthcare providers need to understand: - Who their consumers are? - Where do these consumers live? - What Internet access do they have? - And what is their level of technological literacy? These four considerations are key in helping healthcare providers develop telehealth solutions that are both intuitive and meet their patients’ varying needs. Failure to address these four considerations could lead to telehealth solutions simply not being utilized. Here at France Surgery, we pride ourselves on the transformational telehealth services we provide. It’s our goal to provide our patients with access to SMART healthcare wherever they are and whenever they need it. We understand that what works for one patient won’t necessarily work for another, which is why we never look to take a one-size-fits-all approach.
Newsweek, in collaboration with Statista Inc., has compiled a league table of the world’s best specialized hospitals 2021, and France has no less than 26 Cancer Centers (CLCCs) in the top 200. Topping the list of French oncology hospitals is Institut Gustave Roussy in Villejuif, which ranked fifth in the overall oncology list. Two more French cancer centers – Institut Curie and Hôpital Universitaire Pitié Salpêtrière – were also in the top 50, ranking 12th and 31st respectively. All in all, 26 French cancer hospitals were included in the top 200 global oncology list, highlighting just how renowned these establishments are on the international medical stage. Speaking about the rankings, Jean-Yves Blay, President of Unicancer – the National Federation of French Cancer Centres – said: “We are proud to see that more than half of CLCCs are ranked among the best cancer hospitals in the world. The model of care for cancer patients within the CLCCs is unique and this international recognition underscores the strength and excellence of our network, supported by common values and commitments, at the service of the patient. It also testifies to our constant quest for excellence in healthcare, research and higher education.” For the rankings, Newsweek and Statista surveyed more than 40,000 medical experts from over 20 countries. A global board of experts was then asked to review and rank the hospitals outlined in the survey. You can check out the full Newsweek oncology ranking here.
The impact of the global Covid-19 pandemic has been monumental. But for physicians, nurses and other healthcare practitioners, it’s been particularly difficult. In addition to carrying out their already demanding day jobs, these individuals have had the added stress of coping with social distancing and a surge in patient numbers. It is, therefore, no wonder that a significant proportion of NHS staff in England are concerned about burnout. While it’s not often considered when talking about the benefits of telehealth, such solutions can actually help reduce the risk of physician burnout. Here’s how: - Telehealth helps improve physician work-life balance - Telehealth makes for more optimized schedules - Telehealth reduces the need to commute - Telehealth can help improve physician-patient relationships - Telehealth helps address healthcare coverage gaps, meaning physicians don’t after to overstretch themselves - Telehealth solutions allow physicians more time to look after themselves Healthcare provider burnout is a serious issue. If the very people whose jobs it is to look after us fall ill themselves, how will it bode for the rest of us? You can find out more about the telehealth services provided by us here at France Surgery by contacting us today.
The wider adoption of telemedicine has been one of the most prominent changes to come out of the Covid-19 pandemic. Indeed, data shows that usage of telehealth services has increased by more than 2,000% since last year. Now, new research shows that the vast majority of gastroenterologists are planning to use telehealth more going forward. According to the survey presented at the annual American College of Gastroenterology (ACG) 2020 conference, up to 91% of gastroenterologist respondents say they plan to integrate telehealth into their practice following the COVID-19 pandemic. Furthermore, the survey revealed that gastroenterologists typically view telehealth in a positive light, with 75% of survey respondents reporting their experience of telehealth solutions has been positive. Only 6% reported a negative experience. As many as 63% of gastroenterologists also said they felt telehealth was more efficient than traditional visits, while 58% considered adding telehealth visits between endoscopic procedures. In terms of barriers to telehealth adoption, the biggest for gastroenterologists was the inability to conduct a physical exam, cited by 44.1%. For 27% of gastroenterologist respondents, this barrier was considered critical. Around two-thirds of respondents said their adoption of telehealth solutions would depend on whether the medium would be covered by appropriate insurance payments (equal to in-person consultations). You can find out more about the telehealth services provided by us here at France Surgery by contacting us today.
Since the onset of the Covid-19 pandemic, the number of patients utilizing telehealth solutions has increased significantly. But with telehealth set to remain a mainstay of healthcare going forward, it begs the questions of what are the pros and cons of telehealth? We’ve listed some of each below to help you make an informed decision. Advantages of telehealth for patients: - Patients can typically get an appointment sooner - Appointments are carried out in the safety of a patient’s home or workplace — saving time and money on gas and parking - Telehealth allows elderly patients and those with reduced mobility, as well as people in rural locations, continued access healthcare services - Telehealth services are designed to be easy to adopt - Recent Medicare rule changes in the United States mean that people in more states are covered and can take advantage of telehealth services as part of their health plans - Telehealth services can often be used via a smartphone - A great way to satisfy post-surgical follow-ups Advantages of telehealth for healthcare providers: - More free time to help the neediest patients - Less overcrowding in doctor’s practices - Easier to implement social distancing guidelines Disadvantages of telehealth: - Not suitable for emergency situations (although tele-ICUs are a thing) - Not suitable for when a clinician needs to physically interact with a patient - Unsuitable for routine vaccinations - Not as intimate as a traditional face-to-face appointment If you’d like to find out more about the telehealth services provided by France Surgery, please get in touch.
The US is entering its annual cold and flu season, but this year there’s the added danger of Covid-19 to contend with. Healthcare providers often struggle to meet the needs of their patients at this time of year, mainly because of increased footfall at their facilities. Add to this the strict social distancing guidelines that are in place across the world and the difficulty of the situation becomes clear. The good news is that more and more care providers are turning to telehealth solutions to help alleviate the flu season rush, as well as adhere to social distancing rules. With telehealth, doctors and physicians can carry out consultations with patients without either having to travel. When diagnosing a patient with the flu, physicians look for the two most common symptoms: a cough and fever. At the height of the flu season, almost every patient presenting with these symptoms will have the flu, which often means an in-person consultation is not necessary in the first instance. Care providers can quickly assess a patient’s symptoms via a virtual consultation and arrange to have a prescription sent to them, saving time and money. While every patient’s case is unique, the ability of telehealth to enable physicians to carry out initial consultations for individuals with flu-like symptoms remotely means the facility’s resources are not impacted. This frees up vital appointment slots for those who need them most and reduces wait times, all the while eliminating the chances of someone contracting Covid-19 or spreading flu while out of their house. If you’d like to find out more about the telehealth services provided by France Surgery, please get in touch.
In a previous blog post — what is telehealth? — we wrote about telehealth services and some of the benefits they afford. Today, we are going to follow on from that post by looking at how telehealth has come into its own during the ongoing pandemic. The COVID-19 crisis has meant that millions of people all over the world have had to stay at home, observe social distancing guidelines, and not make any unnecessary trips. But what do you do if you need medical advice or a check-up by your doctor in the middle of a pandemic, with such restrictions in place? Well, according to new research, many seniors are turning to telehealth services so they can keep abreast of their medical needs at this difficult time. In fact, the figures from healthinsurance.com show that overall use of telemedicine services among seniors has increased by a whopping 300% during the COVID-19 pandemic. Furthermore, 30% of survey respondents said they have used telehealth services at least once a month since the COVID-19 crisis occurred. The beauty of telehealth services, such as virtual doctor appointments, is that they are all conducted via the Internet or telephone. Therefore, the patient does not even need to leave the comfort of their home to get a medical opinion — a reality that is particularly beneficial for vulnerable seniors. Want to find out more about the various telehealth services France Surgery provides? Contact us today. We’d love to hear from you.
Throughout the COVID-19 pandemic, you will have likely heard about ‘telehealth’ and ‘telehealth services’. But what is telehealth and how can telehealth services benefit you? In a nutshell, telehealth is the term used to describe healthcare services provided remotely by video or telephone. So if you spoke with your doctor via the Internet using Skype or a similar tool, you would be taking advantage of telehealth services. Another example of telehealth could be if you used an online patient portal to send your healthcare professional some images or records. The goals of telehealth are numerous, but some of the primary desired outcomes include: To make healthcare accessible to people who live in rural or isolated communities To make healthcare accessible to people who have limited mobility, time or those who do not like venturing out of their houses To provide easier and faster access to medical professionals To help enforce social distancing requirements To allow individuals to self-manage their healthcare needs To enable more intuitive collaboration between healthcare professionals to afford better outcomes for patients Even after the COVID-19 pandemic is over, we can expect telehealth services to remain a core part of healthcare going forward. If you’d like to find out more about the telehealth services provided by France Surgery, please get in touch.
While the COVID-19 lockdowns across Europe have not been easy for most people, new research shows that they have been effective in saving countless lives. According to the study by a team at Imperial College, London, Europe-wide lockdowns to reduce the impact of SARS-CoV-2 have saved more than three million lives. The team said that if lockdown had not been implemented across the continent, the “death toll would have been huge”. However, the team also warned that Europe is still only at the beginning of the pandemic and that scores more people could be infected. Assessing the impact of lockdowns up to the beginning of May in 11 European countries: Austria, Belgium, Denmark, France, Germany, Italy, Norway, Spain, Sweden, Switzerland and the UK. By that time, approximately 130,000 people had died from COVID-19 in those countries. Using disease modelling, the researchers predicted how many deaths there would have been if no lockdowns and restrictions had been enforced. They estimated 3.2 million people would have died by 4 May, the report in the journal Nature shows. In other words, lockdown measures prevented around 3.1 million lives, including 470,000 in the UK, 630,000 in Italy and 690,000 in France. "Lockdown averted millions of deaths, those deaths would have been a tragedy," said Dr. Seth Flaxman, from Imperial College. [Related reading: Which demographic worries least about COVID-19?]
As the number of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases globally passes 3.5 million, world leaders have pledged more than $8bn (€7.3bn) to help with the development of a coronavirus vaccine and fund research into diagnosing and treating the disease. The donations came from more than 30 countries, as well as numerous UN and philanthropic bodies and research institutes. Pop singer Madonna was one of the donors, pledging $1.1m (€1m), while Norway matched the European Commission’s contribution of $1bn (€920m) and France, Saudi Arabia and Germany all pledged $500m (€458m). Japan promised to give more than $800m (€733). Russia and the United States, which has suspended funding to the World Health Organization, were notably absent from the online summit hosted by the European Union (EU). Meanwhile, China, where SARS-CoV-2 originated in December, was represented by its ambassador to the EU. The EU said that $4.4bn of the money raised will go towards developing a vaccine, $2bn on the search for a treatment and $1.6bn for producing tests. In an open letter published in newspapers over the weekend, French President Emmanuel Macron and German Chancellor Angela Merkel said the pledged funds would “kickstart an unprecedented global co-operation between scientists and regulators, industry and governments, international organizations, foundations and healthcare professionals”. “If we can develop a vaccine that is produced by the world, for the whole world, this will be a unique global public good of the 21st Century,” they added. [Related reading: How long before there’s a coronavirus vaccine?]
The Mediterranean diet, which features plenty of vegetables, fruits, herbs, nuts, beans and whole grains, has long been lauded for its heart health benefits. But now a new study shows that it could also improve brain function in elderly people, even when only eaten for a year. According to the research published in the BMJ, following a Mediterranean diet for just 12 months can inhibit production of inflammatory chemicals in elderly individuals that can lead to loss of cognitive function, as well as prevent the development of chronic diseases such as diabetes, cancer and atherosclerosis. For the study, 612 elderly people from France, Italy, the Netherlands, Poland and the United Kingdom has their gut microbiome analysed. Then, 323 of them were put on a special diet, based on Mediterranean principles, for one year, while the rest were asked to eat as they normally would. After 12 months, all of the study participants had their gut microbiome re-analysed. Those who had followed the Mediterranean diet saw beneficial changes to the microbiome in their digestive system. The rate at which bacterial diversity was lost slowed and the production of potentially harmful inflammatory markers was reduced. Furthermore, there was also a growth of beneficial bacteria linked to improved memory and brain function. So-called “keystone” species, critical for a stable “gut ecosystem”, were also boosted, helping to slow signs of frailty, such as walking speed and hand grip strength. “Our findings support the feasibility of changing the habitual diet to modulate the gut microbiota which in turn has the potential to promote healthier aging,” the study authors said.
Americans have more than 600,000 knee replacements every year and that number is expected to increase to 1.28 million by 2030, according to the American Academy of Orthopaedic Surgeons (AAOS). But despite the high numbers, many individuals wait too long to undergo surgery, and can miss out on some of the potential benefits, a new report reveals. The report, published in the Journal of Bone and Joint Surgery in January, 2020, shows that 83% of patients with osteoarthritis in their knees wait too long to have a replacement. As a result, these patients don’t get as much function back after surgery as patients who undergo a knee replacement in a timely fashion. Furthermore, patients who wait too long to have knee surgery also place themselves at risk of developing other health conditions like depression. This is due to the fact their mobility is severely hindered, making exercise and physical activity difficult. But having knee replacement surgery too early can also lead to issues. By having knee replacement surgery too soon, patients put themselves at risk for complications and may need a revision surgery later in life. Revisions are typically more difficult and can result in poorer outcomes. The study highlights just how important it is to consult a medical professional when you are experiencing problems with your knees and undergo surgery in a timely fashion. For more information on how France Surgery can facilitate knee replacement surgery for you right here in France, contact us today.
Le diagnostic précoce est l'un des facteurs clés dans la prévention et le diagnostic d'un grand nombre de maladies qui ne présentent pourtant aucun symptôme apparent chez le patient. Les bilans des santé proposés par notre partenaire espagnol, Quironsalud, se focalisent sur une exploration complète, multidisciplinaire et personnalisée, adaptée au sexe, âge et antécédents personnels du patient. A quel moment faut-il faire un check-up ? Des examens médicaux réguliers sont recommandés pour tous ceux qui veulent prendre en main leur santé et pour qui la détection des facteurs de risque dans les meilleurs délais est une priorité. Chez Quironsalud, en une journée, vous pourrez suivre un bilan de santé complet grâce à une coordination et un parcours de soins conçu spécifiquement à cet effet, pour le confort du patient et de son entourage. Les bilans de santé proposés par Quironsalud s’adressent à chacun d’entre nous. Que vous soyez en bonne santé, que vous souffriez d’une maladie chronique ou que vous présentiez certains symptômes bien spécifiques, les équipes médicales des établissements de santé QuironSalud sauront vous proposer le bilan personnalisé adapté à vos besoins. Dans cas, comme par exemple pour des patients souffrant de cancer ou de maladies cardiovasculaires, un contrôle périodique peut vous être proposé pour vous permettre de suivre au plus près l'évolution ou la rémission de votre pathologie. Si vous adoptez le programme patient international proposé par le groupe QuironSalud, tout sera mis en œuvre pour faciliter l’organisation de vos consultations, y compris, l’aide à la planification du voyage, facilitation pour l’obtention du visa, prise en charge à l'aéroport/gare et le transfert à la clinique ou à votre hôtel. Un service de traduction est à aussi à votre disposition ainsi qu'un accompagnateur qui sera à votre écoute tout au long de votre séjour au centre médical Quironsalud. Pour plus d'informations, contactez-nous dès maintenant au : firstname.lastname@example.org ou par téléphone au +33 953 02 03 09.
Gum disease is linked to an increased risk of hypertension, a new study has found. Furthermore, the more sever the gum disease, the greater a person’s risk of high blood pressure. The research by University College London's Eastman Dental Institute – the findings of which appear in the journal Cardiovascular Research – shows people with periodontitis (an advanced form of gum disease) have a higher risk of hypertension. Hypertension, according to the Centers for Disease Control and Prevention (CDC), affects 32% of all American adults, and as many as 47.2% of people aged over 30 have some form of gum disease, which is why the new research is so intriguing. While the two conditions may appear to be completely unrelated, the new research shows otherwise. And when you consider that high blood pressure is the leading cause of premature death worldwide, affecting up to 45% of adults, the findings of the study could result in much more attention being paid to combatting gum disease going forward. Specifically, the research revealed an association between moderate-to-severe periodontitis and a 22% higher risk of hypertension, Moreover, severe periodontitis was linked to a 49% higher risk of hypertension. Speaking about the findings of their research, senior author Prof. Francesco D'Aiuto, from the University College London Eastman Dental Institute in the United Kingdom, said: “Previous research suggests a connection between periodontitis and hypertension and that dental treatment might improve blood pressure, but to date, the findings are inconclusive. “Hypertension could be the driver of heart attack and stroke in patients with periodontitis,” he added.
Hip and knee replacements last much longer than previously thought, according to a large-scale study from the UK. It’s a reality that will help both patients and surgeons determine when it is the right time to perform surgery. The study conducted by the University of Bristol analysed 25 years’ worth of operations data involving more than 500,000 patients. It found that eight out of 10 knee replacements (80%) and six out of 10 hip replacements (60%) last as long as 25 years. Until now, little has been known about the true success and longevity of replacement hips and knees – despite them being two of the most common forms of surgery carried out on the NHS. Previously, doctors have been unable to provide accurate estimates as to how long a patient’s replacement hip or knee might last. Now, they are in a much better position to give confident answers when questioned. Speaking about the findings of the research, which were published in The Lancet, Dr Jonathan Evans, orthopaedic registrar, lead study author and research fellow at Bristol Medical School, said: “At best, the NHS has only been able to say how long replacements are designed to last, rather than referring to actual evidence from multiple patients' experiences of joint replacement surgery. “Given the improvement in technology and techniques in the last 25 years, we expect that hip or knee replacements put in today may last even longer.” Follow these links to find out more about minimally invasive hip replacement surgery and minimally invasive knee surgery in France.
The New Year is here and for many that means attempting to stick to one or a bunch of resolutions. Eating more healthily, doing more exercise and quitting smoking will be at the top of the list for many people. If one of your goals for 2019 is eating more healthily, perhaps you should consider following a Mediterranean diet. While it varies depending on where you go, a Mediterranean diet, in a nutshell, is one that incorporates all of the healthy eating habits of people who live in countries bordering the Mediterranean Sea, including France, Greece, Italy and Spain - so more vegetables, fruits, beans, legumes, nuts, grains, cereals, fish, and unsaturated fats such as olive oil. And less meat and dairy foods. As well as being linked with better health, including a healthier heart, a Mediterranean diet also promotes healthy brain aging, according to new research. A recent study involving 116 healthy adults aged 65–75 years, conducted by the University of Illinois at Urbana–Champaign, found that participants who ate a Mediterranean diet performed better in memory, general intelligence, and executive function tests. “Our study suggests that diet and nutrition moderate the association between network efficiency and cognitive performance,” said Aron Barbey, a psychology professor at The University of Illinois.
Christmas Day is less than two weeks away and that means many of us will soon be gorging ourselves on all sorts of culinary delights. It’s a reality that will see a lot of people piling on the pounds this month ahead of the inevitable January fitness drive. But what if there was a simple way to limit the impact of Christmas feasting on our waistlines? A new study by the Universities of Birmingham and Loughborough in the UK suggests there is. According to the study involving 272 volunteers, regular home weigh-ins coupled with simple weight-loss tips can prevent people from putting on weight over the festive period. For the study, the volunteers were divided into two groups. One group weighed themselves regularly and were given dietary advice, including information on how many calories they needed to burn to negate Christmas food. The other group didn’t weight themselves and were only given a small amount of healthy lifestyle advice. The group that weighed themselves and had access to the additional information weighed 0.49kg less than the "comparison" group come the end of the study. Study lead author, Frances Mason, of the University of Birmingham's Institute of Applied Health Research, said “People gain a kilo of weight on average annually. Often this weight gain happens at Christmas, and is never fully lost. This could possibly be a factor driving the obesity epidemic.” In other words, by simply keeping track of your weight and understanding the impact the foods you are eating are having on your waistline, you stand a better chance of avoiding weight gain at a time of year that’s traditionally associated with piling on the pounds. [Related reading: Why being overweight increases your risk of cancer]
Les lauréats du Nobel de médecine 2018, James Allison et Tasuku Honjo, ont révolutionné l’approche pour traiter les tumeurs, en trouvant le moyen d’activer la réponse du système immunitaire. Le Prix Nobel de médecine 2018 récompense l’Américain James Allison et le Japonais Tasuku Honjo, deux chercheurs qui ont développé une approche totalement innovante contre les cancers. De manière isolée, les deux hommes ont trouvé le moyen d’activer le système immunitaire de l’organisme pour l’aider à éliminer lui-même des tumeurs, une technique en plein essor appelée immunothérapie. Cancer: l’immunothérapie cherche à repousser ses limites Jusque-là, les médecins avaient accès à trois voies majeures pour lutter contre les cancers: la chirurgie, la radiothérapie pour irradier les tumeurs et les médicaments s’attaquant aux cellules tumorales, comme la chimiothérapie. Les travaux de James Allison, du centre MD Anderson de l’université du Texas et Tasuku Honjo, de l’université de Kyoto, apportent ainsi une quatrième approche, en stimulant le système immunitaire. Lymphocytes T La clé de l’approche inventée par les deux scientifiques, de manière totalement indépendante l’un de l’autre, repose sur le fonctionnement les lymphocytes T, les cellules responsables de la réponse immunitaire de l’organisme. Dans le cas de la plupart des tumeurs, les lymphocytes T n’arrivent pas à percevoir les cellules cancéreuses comme une menace, et n’essaient même pas de les détruire. Immunothérapie et chimio, une combinaison gagnante contre certains cancers James Allison a découvert un récepteur sur les lymphocytes T, appelé CTLA4, qui agit comme un frein sur leur fonctionnement. Avec un anticorps spécifique ciblant ce récepteur, un anti-CTLA4, Allison a prouvé qu’il pouvait guérir des souris victimes de tumeurs. Un succès spectaculaire qui a par la suite été reproduit chez l’homme, d’abord pour des mélanomes, puis pour bien d’autres types de tumeurs par la suite. De son côté, Tasuku Honjo a découvert une protéine, PD1, qui pouvait elle aussi agir comme un frein pour empêcher les lymphocytes T d’agir. Indépendamment des travaux d’Allison, le chercheur japonais a lui aussi trouvé un moyen d’inhiber PD1, permettant aux cellules du système immunitaires de s’attaquer efficacement à des mélanomes, puis à de nombreuses autres tumeurs. Cyrille Vanlerberghe, Le Figaro France
Sancheng Digital, Europe to China marketing company and France Surgery, France's leading medical tourism company signed a partnership deal this week. The signing took place at TBSeeds - Toulouse Business School's start-up incubator. (Sancheng Digital and France Surgery have strong links to Toulouse Business School, the founders of both companies having studied at the institution.) Chinese outbound medical tourism is growing year on year as Chinese consumers seek to access medical treatment unavailable to them in their home country. Hanya Cao co-founder Sancheng Digital: "Sancheng Digital are excited to be working hand in hand with France Surgery to enable them to strengthen their position in the Chinese market." Carine HILAIRE co-founder France Surgery: "Sancheng Digital's expertise in China focused marketing made them a perfect business partner for France Surgery in our quest to build strong relationships with Chinese clients." Annexe: “Chinese outbound tourism figures continue to grow. Estimates show 500,000 outbound Chinese medical travellers spend at least $10 billion a year, lucrative for medical tourism destinations in Southeast Asia, Europe and the USA.” https://www.imtj.com/news/130m-chinese-holiday-abroad-outbound-medical-tourists-estimated-05m/ Sancheng Digital和France Surgery签署战略合作协议 2018年9月11日，Sancheng Digital 和 France Surgery 在法国图卢兹商学院创业孵化中心签署了一项重要合作协议。Sancheng Digital立足法国南部，致力于中欧贸易合作和国际市场营销服务。在协议签署后， France Surgury 将在其助力下进一步打开中国境外医疗旅游市场。 据报道，随着中国经济稳步增长，中国出境医疗旅游市场也成为各国看好的新蓝海。医疗体检和疗养旅游深受中国中产阶级青睐，除此之外，在癌症等恶性疾病治疗领域，欧美等国往往拥有更充足的医疗资源和更先进的研发治疗手段，因此也吸引着越来越多的中国患者前往海外接受治疗。 France Surgery的创始人凯莉.希拉里 (Carine HILAIRE) 说: "目前我们已经为许多来自欧美，中东，北非地区的病患提供了系列帮助，中国将会是我们的下一站，很高兴我们能和Sancheng Digital成为战略合作伙伴，相信在他们的支持下，我们能更好的了解中国病人的需求，推广法国的医疗旅游品牌，帮助更多中国病患在法国接受相关治疗，重获健康。"
One in five men and one in six women will develop cancer in their lifetime. That’s one of the stark predictions revealed in a new report from the WHO’s International Agency for Research on Cancer (IARC), which is based in Lyon, France. This year alone, there will be 18.1 million new cases of cancer and 9.6 million people will die with the disease worldwide. This represents a significant increase from 14.1 million cases and 8.2 million deaths in 2012. The report also predicts that by the end of the century, cancer will be the number one killer globally and the single biggest barrier to people living long lives. Looking closely at data from 185 countries, the researchers focussed on 36 different types of cancer. Lung cancer, colorectal (bowel) cancer and female breast cancer are thought to be responsible for a third of all cancer cases worldwide. Researchers have attributed the rise to the world’s growing and ageing population. That’s because more people equals more cancer, and as people get older their cancer risks grow. Moreover, as countries become wealthier, more of the people living in them develop lifestyle-related cancers. Speaking about the report, Dr. Christopher Wild, director of the International Agency for Research on Cancer, said: “These new figures highlight that much remains to be done to address the alarming rise in the cancer burden globally and that prevention has a key role to play.” “Efficient prevention and early detection policies must be implemented urgently to complement treatments in order to control this devastating disease across the world.”
Par Martine Lochouarn Publié le 17/06/2018 à 06:00 INFOGRAPHIE - Un diagnostic précoce de ce cancer permettrait d’améliorer la prise en charge. Au cinquième rang mondial par sa fréquence, le cancer de l’estomac figure en troisième place par le nombre de morts, près de 9 % de tous les décès par cancer. Son incidence varie selon les régions du globe, les ethnies et le niveau de développement. L’Asie de l’Est, Japon, Corée et Chine surtout, est fortement touchée, mais aussi l’Amérique du Sud. «Intermédiaire en Europe de l’Est, son incidence est plus faible en Europe de l’Ouest, à l’exception du Portugal, fortement touché», explique le Pr Tamara Matysiak-Budnik, gastro-entérologue et cancérologue (CHU Nantes). En France, de 6000 à 7000 nouveaux cas sont diagnostiqués chaque année, pour 4500 décès. C’est un cancer du sujet âgé, de pronostic médiocre. En quelques décennies, les progrès de l’hygiène alimentaire ont beaucoup réduit son incidence, qui est aujourd’hui assez stable. «L’association démontrée entre infection par H.pylori et cancer gastrique est aussi forte que celle entre tabac et cancer du poumon.» Pr Tamara Matysiak-Budnik, gastro-entérologue et cancérologue (CHU Nantes) La forme la plus fréquente, qui touche le corps et la partie basse de l’estomac, diminue encore peu à peu, mais les cancers de la jonction estomac-oesophage (cardia) plus rares, augmentent avec l’épidémie d’obésité qui favorise le reflux gastro-œsophagien. Moins de 5 % des cancers sont d’origine génétique. Il s’agit souvent de cancers «diffus», infiltrant l’estomac, de très mauvais pronostic, qui touchent des sujets jeunes. Mais le premier facteur de risque de cancer de l’estomac, c’est l’infection par Helicobacter pylori, responsable de près de 90 % des cas. Cette bactérie acquise dans l’enfance colonise la muqueuse gastrique, le plus souvent sans symptôme. «L’association démontrée entre infection par H. pylori et cancer gastrique est aussi forte que celle entre tabac et cancer du poumon», explique la gastro-entérologue. En France, de 20 à 30 % des individus sont infectés, mais 80 % le sont en Afrique et 10 % dans les pays nordiques. Parmi les personnes infectées, de 2 à 20 % auront un ulcère, et parmi elles 1 % aura un cancer gastrique. «Ce processus complexe de carcinogenèse s’étend sur des décennies et passe par une cascade d’étapes, dont la première, la gastrite superficielle, ne survient pas sans infection par H. pylori, ce qui ne signifie pas que cette infection est suffisante», explique le Pr Matysiak-Budnik. L’excès de sel, de viande rouge, d’aliments fumés, le tabac favorisent aussi ce processus, les fruits et légumes ayant un effet protecteur. Les antibiotiques pour éradiquer la bactérie «L’éradication par antibiotiques de l’infection à H. pylori guérit et fait régresser les gastrites superficielles et la plupart des gastrites atrophiques, prévenant ainsi le cancer de l’estomac.» Comme l’incidence de ce cancer est faible en France, un dépistage sur toute la population ne paraît pas adapté. Mais il existe au Japon, et la Slovénie l’envisage. En revanche, la recherche de H. pylori et son éradication sont indispensables dans les formes héréditaires, chez les parents au premier degré de personnes ayant un cancer gastrique, chez les personnes ayant un ulcère, une gastrique atrophique, précancéreuse, ou ayant subi une ablation partielle de l’estomac pour cancer, et chez celles traitées au long cours par certains médicaments anti-acide, les IPP (inhibiteurs de la pompe à protons). La lésion peut être retirée par endoscopie Si le cancer gastrique a un pronostic médiocre, c’est d’abord à cause de son diagnostic tardif, les cancers précoces ne donnant pas de symptômes. Parfois, une lésion précoce est découverte par des signes très généraux comme une anémie. «Mais le plus souvent ils sont détectés à un stade évolué, parce que surviennent une hémorragie digestive, des douleurs qui ressemblent à un ulcère, un amaigrissement, des difficultés d’alimentation… C’est l’examen endoscopique et la biopsie des lésions qui confirment ce diagnostic, explique le Pr Thomas Aparicio, gastro-entérologue et cancérologue (hôpital Saint-Louis, Paris). Si la lésion est petite et superficielle, elle est parfois enlevée par endoscopie dans des centres très expérimentés. Mais la laparoscopie est moins utilisée que dans le cancer du côlon, et l’ablation chirurgicale se fait le plus souvent en ouvrant l’abdomen.» Le principal progrès de ces quinze dernières années dans l’amélioration de la survie, c’est la chimiothérapie périopératoire, avec en général deux mois de chimiothérapie préopératoire pour réduire la tumeur et éliminer les micrométastases, et deux mois de chimiothérapie postopératoire. Les 30 % de cancers métastatiques d’emblée ne sont pas opérés. Comme pour d’autres tumeurs, ces formes métastatiques commencent à bénéficier des avancées des thérapies ciblées et de l’immunothérapie. Mais, globalement, les progrès sont modestes et les essais souvent décevants. «Notre arme principale reste la détection, le plus précoce possible, qui a un peu progressé puisqu’on identifie 10 % de cancers superficiels précoces, contre 4 % il y a dix ans», insiste le Pr Matysiak-Budnik. De nouveaux tests en cours d’évaluation pourraient aider à améliorer ce dépistage…
As temperatures soar across parts of France, what better time than now to talk about the importance of sun protection? Especially as new research from London suggests people are not getting as much protection from suntan lotions as they could because they are applying them incorrectly. According to researchers from King’s College London, people simply aren’t putting enough suntan lotion on their bodies. The researchers say that SPF15 lotions should, in theory, provide adequate protection, but many people apply them too thinly, which is why, in reality, they need SPF 30 or 50 to be safe. SPF ratings are based on suntan lotion being applied correctly. A 2mg blob should be used to cover 1 sq cm of skin. So, the average person should use around six full teaspoons (36g) to cover their entire body. Extra care should also be taken when applying lotion to areas that get a lot of sun exposure, such as the ears, nose and neck. Furthermore, suntan lotion should be reapplied at least every two hours and immediately after swimming. This is because while many lotions claim to be water resistant, towel drying often removes large quantities. Nina Goad, of the British Association of Dermatologists, said: "This research demonstrates why it's so important to choose an SPF of 30 or more. "It also shows why we shouldn't rely on sunscreen alone for sun protection, but we should also use clothing and shade."
C H E N G D U H E A L T H S E R V I C E C H A M B E R O F C O M M E R C E & S A N Y I M E D I C A L C E N T R E & C H I N A I N T E R N A T I O N A L M E D I C A L T O U R I S M F A I R O U R D E L E G A T I O N The French Medical & Health Delegation, comprised of Dr. Marc Giraud, co-founder of France Surgery and Dr. Jean-Patrick Lajonchère, the President of Hôpital Saint Joseph in Paris, travelled to Chengu, China earlier this month. They were welcomed by Mr. SHI JUN, President of the Chengdu Health Service Industry Chamber of Commerce, together with representatives of JustGood Health Industry Group, Sichuan Southwest International Medical equipment city and Chengdu Yukang hospital. This was a good opportunity to bound the Franco-Chinese partnership related to the medical and health industry, that was signed last November in Paris, when France Surgery, together with Mr. Philippe Douste-Blazy and the Hôpital Saint Joseph welcomed the Chinese delegation. The Chinese tour also comprised a visit at the China International Medical Tourism (Chengdu) Fair and to the Sanyi Medical Center, where we've met esteemed professionals and future collaborators!
France is still woozy with World Cup fever and rightly so (Allez Les Bleus), which makes today’s blog post particularly topical. That’s because a new study has set out to discover whether repeatedly heading a football can cause damage to the brain and lead to long-term health problems. Involving 300 former professional footballers, the study plans to put the ex-players through a series of tests that are designed to assess their physical and cognitive capabilities. Clinical examinations will be performed on the players, all aged between 50 and 85, while additional data relating to their playing careers and lifestyle choices will also be sourced. This is so the study researchers can differentiate between the players’ former positions and draw more accurate comparisons. The footballers’ results will then be compared to available population data relating to individuals born in 1954 who have had their ageing processes monitored since birth. The researchers hope this will allow them to discover if mild concussions in football that often occur when a player heads the ball can have long-term effects. The study will be carried out by the London School of Hygiene and Tropical Medicine (LSHTM), Queen Mary University of London and the Institute of Occupational Medicine. Lead researcher Prof Neil Pearce, from LSHTM, said: “This study will provide, for the first time, persuasive evidence of the long-term effects on cognitive function from professional football.”
INFOGRAPHIE - Un essai clinique a permis de soigner 22 personnes souffrant de bêta-thalassémie, une anémie d’origine génétique. Une collaboration majoritairement franco-américaine a obtenu un beau succès thérapeutique contre une pathologie sanguine, la bêta-thalassémie. Cette maladie génétique est rare en France, avec environ 600 malades, mais elle est bien plus fréquente au sein de certaines populations dans le pourtour méditerranéen, en Asie ou encore en Afrique noire. Elle est provoquée par un défaut dans un gène qui perturbe la production de l’hémoglobine, et qui se traduit par des globules rouges qui ne font plus assez bien leur travail et provoquent des anémies plus ou moins sévères, qu’il faut compenser par des transfusions. Les premiers résultats d’un essai clinique publiés le jeudi 19 avril dans la revue New England Journal of Medicine prouvent l’efficacité d’un traitement de thérapie génique, où les mutations qui provoquent la maladie ont été corrigées dans les cellules des malades. En 2010, un premier malade avait été soigné avec cette technique, et l’essai clinique qui vient de se dérouler sur 22 malades prouve que ce succès n’était pas un cas isolé. Douze d’entre eux n’ont plus du tout besoin de transfusion sanguine, et trois autres ont pu réduire la fréquence de ces injections de globules rouges. Gène correcteur dans les cellules souches L’idée de la thérapie génique, insérer un gène «réparé» dans l’organisme du patient pour soigner sa maladie, a été très largement mise en avant depuis des années, notamment par le Téléthon, mais les vrais succès sont encore rares. «Pour la bêta-thalassémie, j’ai eu l’idée de ce traitement il y a déjà une vingtaine d’années, mais la mise au point a été très longue, très difficile», reconnaît le Pr Philippe Leboulch, haut conseiller pour l’innovation médicale de la direction de la recherche fondamentale du CEA. Les premiers tests réussis sur des souris avaient été publiés il y a dix-sept ans dans la revue Nature, et le passage à une technique efficace chez l’homme a été long. La bêta-thalassémie était dès le départ une cible intéressante, car elle est provoquée par la mutation d’un seul gène. Mais la grande difficulté a été de réussir à corriger ce gène dans le corps du malade, et plus précisément dans les cellules souches dites hématopoïétiques, les «usines» qui produisent en continu les cellules sanguines de l’organisme. Traitement moins lourd pour le malade C’est ce scénario idéal qui s’est produit pour 12 des 22 patients traités, dont certains dans le service du Pr Marina Cavazzana à l’hôpital Necker-Enfants malades à Paris, en collaboration avec l’institut Imagine (AP-HP/Inserm/Université Paris-Descartes). Les cellules génétiquement corrigées qu’ils ont reçues se sont bien implantées, et ont permis de produire suffisamment d’hémoglobine saine pour qu’ils n’aient plus besoin de recevoir des transfusions sanguines régulières. « J’ai bientôt 24 ans et j’ai bénéficié d’une autogreffe il y a quatre ans, témoigne une patiente du Pr Marina Cavazzana. Grâce à ça, aujourd’hui, je n’ai plus de transfusion mais surtout plus de Desféral, qui était mon traitement afin de descendre ma ferritine.» Le Desféral est un traitement contre l’effet délétère des dépôts de fer causés par ces transfusions. Dernier avantage, ce traitement est moins lourd pour le malade que les greffes de moelle osseuse, qui ne sont d’ailleurs possibles que dans 25 % des cas.