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Osteoporosis drugs linked to 34% lower risk of premature death

15/08/2019

Osteoporosis is a disease that causes bone quality and density to decline over time. As a result, people with osteoporosis are at greater risk of fracturing bones. And it’s often not until a fracture occurs that an individual realises they have osteoporosis. That’s because the disease affects bones silently and progressively, with few symptoms. Following a fracture, osteoporosis patients are often prescribed medication to help support their bone health. Common osteoporosis drugs include etidronate and nitrogen bisphosphonates (usually alendronate and risedronate). Now, new research has revealed just how effective these drugs are. According to two different studies conducted by the Garvan Institute of Medical Research in Darlinghurst, Australia, osteoporosis drugs not only reduce the risk of further fractures, but also decrease a person’s risk of premature death. In the first study, the research team analysed data relating to over 6,000 osteoporosis patients aged 50 and over. They found that people taking alendronate had a 34% lower risk of premature death. For the second study, the researchers looked specifically at how nitrogen bisphosphonates impact bone loss and mortality risk in women aged 50 and over. They found that patients who took nitrogen bisphosphonates had both a lower rate of bone loss and a lower mortality risk. However, the studies also revealed that many osteoporosis patients do not follow their drug prescriptions and neglect to take the necessary drugs. Speaking about the findings of the two trials, lead author Dana Bliuc, Ph.D. said: “For many individuals with osteoporosis, bone health isn't front-of-mind. We hope our study results will encourage people with osteoporosis or at risk of a fracture to seek treatment — and commit to taking it.” So the advice is clear: if you have been prescribed osteoporosis drugs, make sure you take them as directed.

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