Following a low-calorie diet – even for just a few months – can arrest type-2 diabetes for at least two years, new research suggests. The findings of the study highlight that type-2 diabetes might not necessarily be the life sentence we previously thought. Nearly 300 people with type-2 diabetes in Scotland and Tyneside (in the UK) participated in the study. Half were given standard diabetes care, while the other half were put on a structured weight management programme. After 12 months, 46% of those on the low-calorie programme had successfully reversed their type-2 diabetes. In comparison, just 4% of the study participants given the standard treatment had gone into remission. Two years later, 36% of the study participants on the structured weight management programme were still in remission. “People with type 2 diabetes and healthcare professionals have told us their top research priority is: ‘Can the condition be reversed or cured?’ We can now say, with respect to reversal, that yes it can. Now we must focus on helping people maintain their weight loss and stay in remission for life,” said Prof Mike Lean from Glasgow University, who led the study with Taylor. Type-2 diabetes causes blood sugar levels to rise and can lead to serious complications such as amputations, visual problems and heart disease. It is thought that one in 16 adults in the UK is currently living with type-2 diabetes, a condition that is fuelled by obesity. [Related reading: Why being overweight increases your risk of cancer]
The health benefits of eating fiber have long been hailed, but how much fiber should we all be eating to prevent chronic disease and premature death? A new study reveals just that… Commissioned by the World Health Organization (WHO), the research is the culmination of a meta-analysis of observational studies and clinical trials that took place over almost 40 years. The results appear in the journal The Lancet. One of the objectives of the research was to help in the development of new guidelines for dietary fiber consumption, as well as discover which carbs protect us the most against noncommunicable diseases. So how much fiber should we be eating? Well, the research found that a daily intake of 25–29 grams of fiber is ideal. People who consumed this amount of fiber each day were 15–30 percent less likely to die prematurely from any cause and had a 16–24 percent lower incidence of stroke, coronary heart disease, type 2 diabetes, and colon cancer. The researchers also say that consuming more than 29 grams of fiber per day could lead to even more health benefits. Speaking about the findings of the study, Professor Jim Mann, of the University of Otago, in New Zealand, said: “The health benefits of fiber are supported by over 100 years of research into its chemistry, physical properties, physiology, and effects on metabolism. “Fiber-rich whole foods that require chewing and retain much of their structure in the gut increase satiety and help weight control and can favorably influence lipid and glucose levels. “The breakdown of fiber in the large bowel by the resident bacteria has additional wide-ranging effects including protection from colorectal cancer.” Fiber-rich foods include vegetables, whole grains, fruit, and pulses, such as beans, peas, lentils, and chickpeas. Are you consuming enough fiber?
How’s your blood pressure? Do you even know? If you haven’t had it checked recently, your blood pressure could be creeping up (getting higher) and you might not have even realised. In fact, high blood pressure (also known as hypertension) is often called a “silent killer” because it rarely causes symptoms until a person’s health is already severely damaged. That’s why keeping an eye on your blood pressure and looking out for any potential symptoms is so important. Failure to seek treatment when you have high blood pressure can lead to serious health complications such as stroke and heart disease. This is ironic when you consider that hypertension can usually be treated with lifestyle changes and/or medication. So what high blood pressure warning signs should you be looking out for? First and foremost, the only way to check whether you have high blood pressure or not is to have it checked by a health professional, or check it yourself providing you know how to and have the necessary equipment. Remember, just because you feel ‘fine’ does not mean you aren’t at risk of hypertension. If your blood pressure becomes extremely high (above 180/120 mmHg), something referred to as ‘hypertensive crisis’, you may experience any of the following symptoms: Severe headaches Nosebleeds Severe fatigue Chest pain Irregular heartbeat Vision problems Back pain Severe anxiety Blood in your urine Shortness of breath (difficulty breathing) Hypertensive crisis is a medical emergency and immediate intervention is required to prevent serious damage to blood vessels and major organs. So, in short, you are unlikely to know whether you have elevated blood pressure or not until serious damage has occurred. Get your blood pressure checked regularly and heed any advice from medical professionals on how to keep yours at a healthy level.
According to the World Health Organization (WHO), obesity is a “global epidemic” that must be tackled if we are to prevent its ill effects. In the United States, nearly 40% of adults and 18.5% of children aged 2 to 19 are obese. Obesity is a major risk factor for type-2 diabetes, heart disease and some types of cancer. That’s why finding effective ways to treat the condition is paramount. But now scientists say they are on the verge of creating a pill that could make obesity a thing of the past - without the need for diet and exercise. Sounds too good to be true, right? Nevertheless, the team at Flinders University in South Australia say that they key to curbing obesity could lie in a single gene known as RCAN1. The team found that when RCAN1 was removed in mice and they were then fed a high fat diet, they did not gain weight. In fact, they could eat as much food as they wanted over a prolonged period of time, the researchers say. Damien Keating, Ph.D., professor of molecular and cellular physiology at Flinders, and leader of the research team, said blocking RCAN1 allows the body to transform unhealthy white fat into calorie-burning brown fat. Stunning pictures of the mice used for the trial highlight the difference when RCAN1 was blocked and when it wasn’t. The results of the research are published in the journal EMBO Reports.
Strength training exercises benefit the heart more than aerobic activities, such as walking and cycling, new research suggests. The survey of more than 4,000 American adults found that static exercise, like lifting weights, is more effective at reducing the risk of heart disease than cardiovascular exercise. Specifically, while undertaking both static and dynamic exercise was associated with a 30% to 70% reduction of cardiovascular risk factors, the link was strongest for younger individuals who did static exercises. Nevertheless, any amount of exercise brings benefits and doing both static and dynamic types is still better than focussing on just one kind, the researchers from St. George's University in St. George's, Grenada said. Speaking about the findings of the research, Dr. Maia P. Smith, assistant professor at the Department of Public Health and Preventive Medicine at St. George's University, said: “Both strength training and aerobic activity appeared to be heart healthy, even in small amounts, at the population level.” Current American Heart Association (AHA) guidelines recommend that American adults should undertake at least 150 minutes of heart-pumping physical activity every week. The same guidelines also stipulate that said activity should be spread across the week and not completed in just one or two days. Are you doing enough physical activity each week? If not, you could be increasing your risk of cardiovascular disease. [Related reading: Why being overweight increases your risk of cancer]
A new study, one of the largest of its kind, suggests being the wrong weight i.e. overweight or underweight cold knock four years off a person’s life expectancy. According to the study, the findings of which were published in the Lancet Diabetes and Endocrinology journal, from the age of 40, people towards the higher end of the healthy Body Mass Index (BMI) range (a healthy BMI ranges from 18.5 to 25) had the lowest risk of dying from disease, including cancer and heart disease. In contrast, individuals who had BMI scores of less than 18.5 or more than 30 had life expectancies that were 4.4 years and 3.85 years shorter respectively. BMI scores, which are calculated by dividing a person’s weight (in kilograms) by their height (in metres squared), are still considered by health professionals to be the simplest and most accurate way to work out if someone is overweight or underweight. For the population-based cohort study, researchers analysed anonymised data on 3.6 million adults from the U.K. Clinical Practice Research Datalink (CPRD). Dr Krishnan Bhaskaran, lead author of the study, said: “The most striking thing about our findings was how widely BMI was linked to different causes of death. BMI was associated with deaths from nearly all major causes.” He added that the research reinforces the importance of maintaining a healthy body weight. Perhaps the most interesting finding is that people who have low BMI scores are at as much risk, if not more, of reducing their life expectancies.
Do you take supplements containing omega-3 fish oil in the belief they are helping to protect your heart? A new study suggests you could be wasting your money. Researchers from Cochrane analysed trials involving more than 100,000 people and discovered little proof that omega-3 supplements prevented heart disease. In fact, they say the chance of getting any benefits from such supplements is one in 1,000. However, despite this, the researchers still maintain that eating oily fish as part of a healthy diet is beneficial. Indeed, NHS guidelines state that people should try to eat two portions of fish each week, one of which, ideally, should be oily fish such as mackerel, salmon or fresh tuna. This is so they get enough “good” fats. Speaking about the findings of the research, Prof Tim Chico, a cardiologist from Sheffield University, said: “There was a period where people who had suffered a heart attack were prescribed these on the NHS. This stopped some years ago. “Such supplements come with a significant cost, so my advice to anyone buying them in the hope that they reduce the risk of heart disease, I'd advise them to spend their money on vegetables instead.” Dr Lee Hooper, from the University of East Anglia, said: “The most trustworthy studies consistently showed little or no effect of long-chain omega-3 fats on cardiovascular health.” Nevertheless, Dr Carrie Ruxton from the UK’s Health and Food Supplements Information Service said supplements containing omega-3 can still play an important role for people who don’t eat oily fish – especially as omega-3 also benefits the brain, eyes and immune function.
Doctors should take a person’s marital status into account when assessing their risk of heart attack and stroke, a major study has found. For the study, researchers at Keele University analysed numerous trials involving more than two million people. They found that individuals who were never married, divorced or widowed were 42% more likely to develop cardiovascular disease. They were also 42% more likely to die from heart disease and 55% more likely to die from a stroke. Risk factors such as age, sex, high cholesterol, high blood pressure, smoking, and diabetes are usually associated with cardiovascular disease. However, the findings of the new study suggest marital status should also be added to the list. Senior author, Mamas Mamas, Professor of Cardiology at Keele University, in England, said: “Our work suggests that marital status should be considered in patients with or at risk of developing cardiovascular disease, and should be used alongside more traditional cardiac risk factors to identify those patients that may be at higher risk for future cardiovascular events”. The researchers say the reason marriage could have a protective effect on cardiovascular disease is because of the additional emotional and social support that’s afforded by having a spouse. People with long-term partners are more likely to have symptoms spotted earlier and encouraged to seek medical advice as a result.
Most people are familiar with the phrase, ‘an apple a day keeps the doctor away’, but what about an egg a day? New research suggests that a daily egg may reduce the risk of heart disease and stroke. Despite sometimes getting a bad press for their high cholesterol content, eggs, it seems, could help us steer clear of cardiovascular conditions, according to research published in the journal Heart. For their study, researchers from the School of Public Health at Peking University Health Science Centre in Beijing, China analysed survey data relating to more than 500,000 individuals. Of those individuals, 461,213 were free from cancer, cardiovascular disease (CVD) and diabetes at baseline. Egg consumption among the study participants was noted and the individuals were followed up with after a median period of 8.9 years. The researchers' found that individuals who usually ate about one egg per day had a 26% lower risk of experiencing hemorrhagic stroke; a 28% lower risk of death due to this type of event; and an 18% lower risk of CVD-related mortality. Current NHS guidelines in the UK relating to egg consumption state: "although eggs contain some cholesterol, the amount of saturated fat we eat has more of an effect on the amount of cholesterol in our blood than the cholesterol we get from eating eggs". So, in other words, it’s not eggs that are necessarily the problem when it comes to cholesterol, but rather how you cook them. Indeed, eggs are a great source of healthful nutrients, such as protein, vitamins, phospholipids, and carotenoids.
Are you a night owl or a morning person? A new study suggests that it could make a big difference to your health and it’s not good news for late risers. According to the paper authored by Dr Kristen Knutson and Professor Malcolm von Schantz, of Northwestern University (Chicago) and the University of Surrey (UK) respectively, night owls have an increased risk of early death, psychological disorders and respiratory illness than people who are, so to speak, up with the lark. The paper backs up previous research that suggests people who regularly go to bed late are more likely to suffer ill health. Over a six-year period, night owls were found to have a 10% greater risk of death than larks, according to the paper. This finding held true even after adjusting for expected health problems in people who go to bed late, such as metabolic dysfunction and heart disease. Using data extracted from the UK Biobank, a data store containing medical and genetic information relating to some 500,000 people aged 40 to 69 from across the UK, the researchers were able to determine the effect a lack of sleep has on individuals. While night owls often make up for their lack of sleep during the week by staying in bed longer at weekends – referred to as “social jet lag” - it is seemingly not enough to combat the potential health problems they face. Commenting on the findings of the research, Dr Knutson said that “night owls trying to live in a morning lark world may have health consequences for their bodies. They shouldn’t be forced to get up for an 8am shift. Make work shifts match people’s chronotypes. Some people may be better suited to night shifts.” Being a night owl was also associated with psychological stress, lack of sleep, lack of exercise, eating at the wrong time, and drug or alcohol use. So, if you're someone who regularly goes to bed late and doesn't get enough sleep during the week, maybe it's time to change your habits.
People who regularly drink more than the UK’s recommended alcohol guidelines risk taking years off their lives, a major new report has found. According to the study of some 600,000 drinkers, having 10 to 15 alcoholic drinks every week could shorten a person's life by between one and two years. People who regularly consume more than 18 alcoholic drinks every week could lose four to five years of their lives. UK government guidelines, which were last updated in January 2016, recommend that both men and women should not drink more than 14 units of alcohol each week (equivalent to 6 pints of average strength beer). Previously, the guidelines advised 21 units for men and 14 units for women each week. The authors of the Lancet study say their findings support the UK government’s revised guidelines. Commenting on the study’s findings, Tim Chico, professor of cardiovascular medicine at the University of Sheffield, said: "This study makes clear that on balance there are no health benefits from drinking alcohol, which is usually the case when things sound too good to be true. "Although non-fatal heart attacks are less likely in people who drink, this benefit is swamped by the increased risk of other forms of heart disease including fatal heart attacks and stroke."
While a low sperm count and problems with sperm quality are huge hurdles for couples who are trying to get pregnant, a new study shows that men with low sperm counts are also at increased risk of illness. The study of 5,177 men in Italy found that those with low sperm counts were 20% more likely to have more body fat, more "bad" cholesterol and higher blood pressure – all factors that increase the risk of developing diabetes, heart disease and stroke. They were also 12 times more likely to have low testosterone levels. Dr Alberto Ferlin, from the University of Bresci, who led the study, said: "Infertile men are likely to have important co-existing health problems or risk factors that can impair quality of life and shorten their lives. "Fertility evaluation gives men the unique opportunity for health assessment and disease prevention." The study’s authors say that men with low sperm counts should be actively checked for other potential health problems, which may have a greater chance of being rectified if treated earlier. However, the authors of the study stressed that their findings did not prove that low sperm counts cause metabolic problems, merely that the two are linked in some way.
New research published in the Journal of the American Heart Association shows that waist-to-hip ratio is a better heart attack predictor than body mass index (BMI), with so-called “apple shape” women at greater risk than their male counterparts. According to the research from the George Institute for Global Health, waist-to-hip ratio is an 18% better heart attack predictor than BMI in women and 6% in men. However, the research also found that BMI was linked to heart disease risk in both sexes. For the research, the team from the George Institute in Oxford interviewed nearly 500,000 UK adults aged 40 to 69. They found women who had bigger waists relative to their hips are at more risk of heart attacks than men with similar body shapes. Speaking about the findings of the research, Ashleigh Doggett, senior cardiac nurse at the British Heart Foundation, said: "Considering the large amount of UK participants, this is a very interesting study which highlights that obesity remains a risk factor for heart attacks in both men and women. "Interestingly, it suggests that those of us who are 'apple' as opposed to 'pear' shape, especially women, may be at higher risk of a heart attack.” The researchers say their findings suggest the differences in the way men and women store fat may affect their risk of heart disease. While more research is needed, these findings do support the notion that being “apple shape” (having proportionally more fat around the abdomen) is more hazardous for your health than being “pear shape” (having proportionally more fat stored around the hips. The full findings of the research can be found in the Journal of the American Heart Association.
Just one cigarette a day can increase a person’s risk of heart disease and stroke, a study has found, dispelling the myth that cutting back, not quitting altogether, can eliminate health issues. The study found that just one cigarette a day can increase a person’s chances of heart disease by about 50% and chances of a stroke by 30% than people who have never smoked. The bottom line is that there is no safe level of smoking when it comes to heart disease and stroke. Cardiovascular disease, not cancer, remains the greatest mortality risk for smokers, accounting for approximately 48% of smoking-related premature deaths. And while the number of people who smoke in the UK has been falling, the percentage of people smoking one to five cigarettes a day has been steadily rising, researchers said. However, cutting down on cigarettes is always a good start and people who do so are more likely to quit in the long-run. Prof Allan Hackshaw from the UCL Cancer Institute at University College London, who led the study, said: "There's been a trend in quite a few countries for heavy smokers to cut down, thinking that's perfectly fine, which is the case for things like cancer. "But for these two common disorders, which they're probably more likely to get than cancer, it's not the case. They've got to stop completely." For the study, the researchers at UCL analysed data from 141 separate smoking-related studies and published their findings in the BMJ.
Researchers at an Oxford hospital have developed an Artificial Intelligence (AI) system that can accurately diagnose heart and lung scans. The new AI could lead to more people being diagnosed earlier and prevent patients being sent home when they are still at risk of having a heart attack. It’s though the system will save the NHS billions of pounds by enabling various diseases to be detected much earlier. The heart disease technology will be available to NHS hospitals for free this summer. Currently, cardiologists use a person’s heartbeat to tell if there is a problem. However, even the most experienced doctors get it wrong in one in five cases. This leads to a patient being sent home when they are still at risk of a heart attack or undergoing an unnecessary operation. The AI system can pick up details on the scans that doctors cannot see, resulting in a more accurate diagnosis. So far, the system has been tested in clinical trials and the results aren’t expected to appear in a peer-reviewed journal until later this year. However, one of the system’s developers has said the data shows it greatly outperformed his fellow specialists. The government's healthcare tsar, Sir John Bell, has indicated that AI could "save the NHS". "There is about £2.2bn spent on pathology services in the NHS. You may be able to reduce that by 50%. AI may be the thing that saves the NHS," he said.
We recently reported that childhood obesity rates are 10 times higher today than they were in 1975. This worrying trend is only set to continue unless more is done to tackle obesity in children. So-called “sugar taxes” on soft drinks in various countries around the world and France’s decision to ban unlimited fizzy drinks in restaurants, fast food-chains, schools and holiday camps, are definitely steps in the right direction. Now, hospitals in England have laid out plans to ban the sale of any sweets or chocolate that contain more than 250 calories. Going forward, super-sized chocolate bars will become a thing of the past in hospital vending machines and canteens. In addition, pre-packed sandwiches with more than 450 calories and/or 5g of saturated fat per 100g will also be banned. Hospitals will be given a cash boost to help them facilitate the changes. The decision to ban fattening and sugary food products in hospitals is actually win-win for the National Health Service (NHS). These foods are major contributors to obesity and many other conditions/diseases, such as preventable diabetes, tooth decay, heart disease and cancer – all of which put enormous strain on the health service. Public Health England says hospitals have an "important role" in tackling obesity and not just dealing with the consequences.
Calcium is well-known for its role in promoting healthy bones, but a new study suggests it could also be beneficial for heart health too. Cardiac arrest, or heart attack, is one of the leading causes of death in the United States today. In fact, according to the American Heart Association (AHA), approximately 350,000 out-of-hospital sudden cardiac arrests (SCAs) occur in America every year. Furthermore, almost 90% of people who experience SCA die as a result. The primary cause of SCA is coronary heart disease. However, around 50% of women and 70% of men who die from SCA have no medical history of heart disease, suggesting other significant risk factors are at play. For the study, researchers from the Cedars-Sinai Heart Institute in Los Angeles, CA, analysed data from the Oregon Sudden Unexpected Death Study. They found that the risk of SCA was increased by 2.3-fold for people who had the lowest blood calcium levels (under 8.95 milligrams per deciliter). More importantly, this risk remained after confounding factors, including demographics, cardiovascular risk factors and medication use, were accounted for. Dr. Hon-Chi Lee, of the Department of Cardiovascular Medicine at the Mayo Clinic in Rochester, MN, said: “This is the first report to show that low serum calcium levels measured close in time to the index event are independently associated with an increased risk of SCA in the general population”.
Coronary arteries are the main blood vessels that supply the heart. Sometimes, these arteries can become narrowed or blocked, which can lead to the flow of blood to the heart becoming restricted. A coronary angioplasty is a surgical procedure used to widen blocked or narrowed coronary arteries. You may be surprised to learn that it is carried out using local anaesthetic and did you know that it involves a tiny balloon? The surgeon makes a tiny incision in your groin, arm or wrist and inserts a catheter. This is then guided to your affected coronary artery using an X-ray video. A tiny balloon is then inserted into the artery via the catheter. The balloon is then inflated to squash any fatty deposits against the wall of the artery widening it once more. This allows blood to flow freely again after the balloon is removed. A stent is sometimes also added and enters the artery at the same time as the balloon. It remains in place after the balloon has been deflated and removed to ensure the artery remains in the best possible shape to allow blood to flow freely going forward. The entire procedure only takes around 30 minutes to two hours and most patients are allowed to go home after just one or two days.
Whether you call them love handles or muffin tops, the areas of built up fat that can appear above your waistline are something that many people would love to be able to easily get rid of. A new patch developed by scientists in the US could provide the easy fix people have been looking for. The novel patch delivers fat-browning drugs directly into the areas of fat and converts "bad" white fat into "good" brown fat - not only reducing the amount of excess fat, but also lowering fasting blood glucose levels. Having too much white fat - particularly around the abdominal region - can raise the risk of several health problems, including diabetes and heart disease. So far, the patches have only been trialled on mice, but it’s hoped that they can be developed for human use in the future. Study co-leader Li Qiang, Ph.D., from the Columbia University Medical Center in New York City, said the patches could offer a great alternative to existing drugs that promote fat browning. Their non-invasive nature can reduce side effects. "The nanoparticles were designed to effectively hold the drug and then gradually collapse, releasing it into nearby tissue in a sustained way instead of spreading the drug throughout the body quickly," says study co-leader Zhen Gu, Ph.D., from the University of North Carolina at Chapel Hill and North Carolina State University in Raleigh.
A study by Public Health England looking at the heart health of the nation has found that thousands of men face early death at the hands of a heart attack or stroke. In fact, according to the analysis of 1.2 million people, one in 10 British men has a heart age that’s a decade older than their actual age. Heart disease is the main cause of death among men and the second among women. Public Health England says that 7,400 people will die from heart disease or stroke this month alone. However, most of these deaths are preventable and Public Health England says that just a few small lifestyle changes can have a positive impact. One of the suggestions made was for over 50s to get their blood pressure regularly checked as high blood pressure can be an early sign of a potentially life-threatening condition. Public Health England’s head of cardiovascular disease, Jamie Waterall, urged people not to only start considering their heart health later in life. "Addressing our risk of heart disease and stroke should not be left until we are older", he said. How to improve your heart health: Give up smoking Get active Manage your weight Eat more fibre Eat five portions of fruit and vegetables per day Cut down on saturated fat Cut down on salt Drink less alcohol
People who are overweight or obese, despite appearing medically healthy, are still at increased risk of heart disease, experts warn. The notion that people can be ‘fat but fit’ is being challenged by research published in the European Heart Journal. According to the researchers from Imperial College London and the University of Cambridge, who studied health data relating to more than half a million people in 10 European countries, weight is still a heart disease risk factor even if someone has normal blood pressure, cholesterol and blood sugar levels. The study found that people who appeared healthy, with healthy blood pressure, cholesterol and blood sugar readings, were still 28% more likely to develop heart disease than individuals with health bodyweights. Even more at risk were people who were overweight or obese and had high blood pressure, cholesterol and blood sugar levels. Dr Ioanna Tzoulaki, from Imperial's School of Public Health, said: "I think there is no longer this concept of healthy obese. "If anything, our study shows that people with excess weight who might be classed as 'healthy' haven't yet developed an unhealthy metabolic profile. "That comes later in the timeline, then they have an event, such as a heart attack”. So the advice if you want to maintain a healthy heart is to watch your weight, even if you think you are fit.
Coconut oil is higher in saturated fat than butter, beef dripping and pork lard, and can increase “bad” (LDL) cholesterol. That’s the stark new warning contained in updated advice from the American Heart Association (AHA). A diet high in saturated fat can lead to clogged arteries and an increased risk of heart disease and stroke. Despite coconut oil being commonly sold as a health food and a “healthier” alternative to other saturated fats, the AHA says there are no good studies to support this. In fact, 82% of the fat found in coconut oil is saturated, which is higher than butter (63%), beef dripping (50%) and pork lard (39%). And studies show that like other saturated fats, coconut oil can increase “bad” cholesterol. The AHA says people should watch how much saturated fat they eat and replace some of it with unsaturated vegetable oils, like olive oil and sunflower oil. Dr Frank Sacks, lead author of the AHA advice, said: "We want to set the record straight on why well-conducted scientific research overwhelmingly supports limiting saturated fat in the diet to prevent diseases of the heart and blood vessels." Nevertheless, saturated fat is still an essential part of a healthy, balanced diet and shouldn’t be completely cut out, just limited. In the UK, Public Health England advises that men should eat no more than 30g of saturated fat a day and women no more than 20g a day.
A vaccine that helps lower cholesterol will now be trialled on humans following successful studies in mice. Researchers from the Medical University of Vienna will now test the safety of their experimental treatment – which stops fatty deposits clogging the arteries – on 72 volunteers. If the trials are successful, the vaccine would offer an alternative for people who currently take pills on a daily basis to reduce their risk of angina, stroke and heart attack. Writing about their cholesterol-lowering vaccine in the European Heart Journal, Dr Guenther Staffler and colleagues from The Netherlands Organisation of Applied Scientific Research say it will take many more years of tests before it is known whether the treatment is safe and effective in humans. In studies of mice, the treatment cut low density lipoprotein (LDL) cholesterol (bad cholesterol) by as much as 50% over 12 months and appeared to stop the build-up of fatty deposits in the arteries. Regardless of whether the vaccine becomes available in the future, the researchers were keen to stress that it should not be seen as an excuse for people to avoid exercise and eat lots of high-fat food. Nevertheless, the treatment could be useful for individuals who have high cholesterol due to an inherited condition called familial hypercholesterolaemia.
A study of nearly a million UK adults has found that being married appears to be good for your health, boosting your chances of survival if you have a major heart risk factor, like high cholesterol. All of the individuals involved in the study had high blood pressure, cholesterol or diabetes and the researchers discovered the ones who were married fared much better than those who were single. Dr Paul Carter and colleagues from Aston Medical School presented the findings of their study at the British Cardiovascular Society conference. They believe that having something special in your life is what’s important, rather than simply being married. At the end of their 14-year ACALM study, the researchers found that married men and women in their 50s, 60s and 70s with high cholesterol had a 16% greater chance of being alive than their single counterparts. Dr Carter said: "We need to unpick the underlying reasons a bit more, but it appears there's something about being married that is protective, not only in patients with heart disease but also those with heart disease risk factors. "We're not saying that everyone should get married though. "We need to replicate the positive effects of marriage and use friends, family and social support networks in the same way." Dr Mike Knapton, of the British Heart Foundation, said: "The take-home message is that our social interactions, as well as medical risk factors such as high blood pressure, are important determinants of both our health and wellbeing. "Whether you are married or not, if you have any of the main risk factors for heart disease, then you can call upon loved ones to help you to manage them."
While the association between a lack of exercise and an increased risk of chronic diseases, including type 2 diabetes and heart disease, is well-established, new research shows that just 14 days of physical inactivity can increase a person's risk such conditions. A study by the University of Liverpool found that young, healthy adults who switched from moderate-to-vigorous activity and then to near-sedentary behaviour for just 14 days experienced metabolic changes that could raise their risk of chronic disease and even premature death. Presenting their findings at the European Congress on Obesity 2017 in Portugal, Study leader Dr. Dan Cuthbertson and colleagues said that reducing physical activity for just 14 days led to a loss of skeletal muscle mass in the participants. However, the reduction of physical activity for 14 days also led to an increase in total body fat. Furthermore, said body fat was most likely to accumulate centrally, which the team notes is a significant risk factor for chronic disease. Current guidelines recommend that adults aged 18-64 undertake at least 150 minutes of moderate-intensity physical activity or 75 minutes of vigorous-intensity physical activity every week. However, the Centers for Disease Control and Prevention (CDC) says that fewer than 50% of adults meet these exercise recommendations. Are you doing enough exercise each week? Even just small lifestyle changes can make a big difference when it comes to your risk of chronic disease.
People with non-O blood could be at greater risk of stroke and heart attack, research suggests. Scientists say it's because A, B and AB blood contains higher levels of a blood-clotting protein. The research, which was presented at the 4th World Congress on Acute Heart Failure, analysed studies involving 1.3m people. It found that people 15 in 1,000 people with non-O blood suffered a heart attack, compared to 14 in 1,000 people with O blood. While these figures don't sound that startling at first, when applied to a whole population the numbers become more important. It is hoped that the findings will help doctors better identify who is at risk of developing heart disease. However, Dr Mike Knapton, associate medical director at the British Heart Foundation, said the findings would not have a large impact on the current advice issued by the charity. "Most of a person's risk estimation is determined by age, genetics (family history and ethnicity) and other modifiable risk factors including diet, weight, level of physical activity, smoking, blood pressure, cholesterol and diabetes. "People with a non-O blood group type - AO, BO and AB - need to take the same steps as anyone wanting to reduce their CVD risk." So regardless of your blood type, the advice remains the same: improve your diet, weight, level of physical activity and don't smoke. In addition, manage blood pressure, cholesterol and diabetes too. There's nothing you can do about your blood group, but you can make positive lifestyle changes to reduce your risk of heart attack and stroke.
More than 20 million people in Britain are physically inactive and increasing their risk of heart disease, according to a new report by the British Heart Foundation. The charity has warned that the lack of exercise by such a large proportion of the British population is costing the NHS a staggering £1.2bn each year. Women are 36% more likely than men to be physically inactive, which the report defines as not meeting the UK government's guidelines for physical activity - 150 minutes of moderate to vigorous intensity physical activity and strength exercises on two or more days a week. However, despite the report finding that 11.8 million women were physically inactive compared with 8.3 million men, it is actually men who sit down for longer (78 days a year compared to 74 for women). Furthermore, inactivity levels differ by region. For example, 47% (2.7 million) of people living in the North West of England were found to be inactive, whereas people in the South East had the lowest rate at 34%. Over five million deaths across the world each year are attributed to physical inactivity, making it one of the top 10 leading causes of death. In the UK, physical inactivity contributes to almost one in 10 premature deaths from coronary heart disease each year, as well as one in six deaths from any cause. Dr Mike Knapton, associate medical director at the British Heart Foundation, said: "Levels of physical inactivity and sedentary behaviour in the UK remain stubbornly high, and, combined, these two risk factors present a substantial threat to our cardiovascular health and risk of early death.
Despite the fact the number of people who are overweight or obese has risen over the past 30 years, fewer people are actually attempting to shed weight, according to a new study, the findings of which were published in JAMA. Around two thirds of the adult population in the United States are obese or overweight, putting them at increased risk of heart disease, stroke, diabetes, and other chronic diseases. However, new research has found that even though there has been a significant rise in the number of people who are overweight or obese since the 1980s, the percentage of U.S. adults who are trying to lose weight has fallen. For their research, study co-author Dr. Jian Zhang and her colleagues from the Georgia Southern University, analysed the data of 27,350 U.S. adults aged between 20 and 59 years. The analyses revealed that the rates of overweight and obesity increased by 13%, from 53% in 1988-1994 to 66% in 2009-2014. Furthermore, the researchers also found that the percentage of people who attempted to lose weight over the same period actually dropped by 7%, from 56% in 1988-1994 to 49% in 2009-2014. At present, people are deemed to be overweight or obese depending on their body mass index (BMI). A BMI of 25 to under 30 is considered overweight, while a BMI of 30 or above is considered obese. A healthy diet and regular physical activity are proven to help curb weight gain, which is why we should all make a conscientious effort to watch what we eat and exercise more. [Recommended read: BMI Wrongly Labelling People Unhealthy, Finds New Research]
People should be cautious when purchasing medications online after an investigation uncovered "widespread failings" at some Internet-based providers, the Care Quality Commission (CQC) has said. The independent regulator of health and social care in England inspected 11 internet prescription services in the country and found some "potentially presenting a significant risk to patients". Despite some providers being well-run, others were cutting corners, according to the CQC investigation. For example, two online providers - Treated.com and MD Direct - did little or no checking of patients' identities. In addition, they were guilty of inadequate prescribing and gave no assurances that the clinicians working behind the scenes had the qualifications or relevant skills for the roles they were performing. Talking to BBC Radio 5 Live, Prof Steve Field, the CQC's chief inspector of general practice, said: ""Some of these websites prescribed unlicensed medicines and - even more worryingly - medicines for diabetes, Parkinson's disease, heart disease and Lithium for bipolar disorder." The CQC has now drawn up a set of clear standards for online pharmacies. Going forward, all Internet-based providers must: verify that a patient is who they say they are, such as through a Skype check obtain a comprehensive and up-to-date medical history ensure patients truly understand what medicines they are being given seek permission to contact a patient's GP One of the biggest problems cited with antibiotics being sold online is that some people treat them like sweets. More discipline is needed if we are to prevent the so-called antibiotic apocalypse - where bacteria become resistant to more and more drugs - from happening.
By simply cooking rice the wrong way, millions of people worldwide could be endangering their lives, scientists believe. That's because rice contains traces of the poison arsenic, which stems from industrial toxins and pesticides that can remain in the soil it grows in for decades. In fact, rice contains about 10-20 times more arsenic than other cereal crops because of the way it is grown in flooded paddies. Fortunately, the way people cook rice can have a dramatic effect on the amount of arsenic that finds its way into their bodies. Chronic arsenic exposure has been linked with cancer, diabetes, heart disease and developmental problems, which is why the new research is so alarming. For the BBC TV programme “Trust Me, I’m a Doctor,” Prof Andy Meharg, from Queens University Belfast, tested how three different ways of cooking rice affected the levels of arsenic in it afterwards. In the first method, he used a ratio of two parts water to one part rice. This is the method many people use and sees the water “steamed out” during cooking. It's also the method that resulted in the most arsenic remaining in the rice. In the second method, he used five parts water to one part rice and washed off the excess water. The levels of arsenic almost halved with this method. In the third and final method, he soaked the rice overnight before cooking it. This resulted in the levels of arsenic being reduced by a whopping 80%. "The only thing I can really equate it to is smoking," said Professor Meharg. "If you take one or two cigarettes per day, your risks are going to be a lot less than if you're smoking 30 or 40 cigarettes a day. It's dose-dependent - the more you eat, the higher your risk is."
A Mediterranean-inspired meal with lashings of virgin olive oil may help to protect your heart, according to new research. Cholesterol is carried around the blood by two different types of molecules called lipoproteins: low-density lipoprotein (LDL) and high-density lipoprotein (HDL). You'll most likely know LDL as "bad cholesterol". That's because high levels of LDL can lead to plaque building up in arteries, which can result in heart disease and stroke. HDL, on the other hand, the so-called "good bacteria", actually absorbs cholesterol and carries it to the liver where it is flushed from the body. That's why having high levels of HDL can reduce your risk of heart disease and stroke. Previous research has shown that the Mediterranean diet can protect against the development of heart disease as it improves the lipid profile of HDLs. The new research - which was led by Montserrat Fitó, Ph.D., coordinator of the Cardiovascular Risk and Nutrition Research Group at the Hospital del Mar Medical Research Institute in Barcelona, Spain - aimed to determine whether eating a Mediterranean diet rich in virgin olive oil or nuts over a long period of time would improve the beneficial properties of HDL in humans. Fitó's team randomly selected a total of 296 people who already had a high risk of heart disease and were participating in a separate study. They had an average age of 66 and were assigned to one of three diets for a year. They found that the individuals on the Mediterranean diet enriched with virgin olive oil had improved HDL functions. "Following a Mediterranean diet rich in virgin olive oil could protect our cardiovascular health in several ways, including making our 'good cholesterol' work in a more complete way," said Fitó.
Around 620,000 people in the UK are living with a faulty gene which places them at an increased risk of developing coronary heart disease or sudden death, a charity has warned. To make matters even worse, most of them are totally unaware. According to the British Heart Foundation (BHF), the number of people with the faulty gene hypertrophic cardiomyopathy (HCM) is 100,000 higher than originally thought and could be even higher still in reality. Every week in the UK, approximately 12 seemingly healthy individuals aged 35 or under suffer a sudden cardiac arrest with no explanation. The cause is predominantly undiagnosed heart conditions. The prevalence of inherited conditions is becoming better known, however, the charity warned that as yet undiscovered faulty genes and under-diagnoses mean the real scale is inevitably unknown. A child of someone who has an inherited heart condition has a 50% chance of inheriting it themselves too. Nevertheless, research has helped to uncover many of the faulty genes that cause inherited heart conditions and structured genetic testing services have been developed as a result. However, the medical director of the BHF, Prof Sir Nilesh Samani, said that more research is urgently needed. "If undetected and untreated, inherited heart conditions can be deadly and they continue to devastate families, often by taking away loved ones without warning. "We urgently need to fund more research to better understand these heart conditions, make more discoveries, develop new treatments and save more lives."
Millions of people all over the world struggle with their waistlines. A constant battle that sees them diet, lose weight and then put it all back on again - sometimes more than they had originally. It's a pattern known as "yo-yo dieting", and a new study suggests that it can be hard on the hearts of older women. According to study leader Dr. Somwail Rasla, who's an internal medicine resident at the Memorial Hospital of Rhode Island in Pawtucket (US), "Women with a normal [weight] who experience yo-yo dieting throughout their adult life are at increased risk of sudden cardiac death and coronary heart disease death". Last week's American Heart Association conference in New Orleans heard that older women who are not necessarily overweight, but continue to strive for that so-called "perfect figure", increase their risk of sudden cardiac death by as much as 66%, which is 3.5 times higher than women who maintain a stable weight. It's long been known that being overweight as you reach middle age is linked with a higher risk of mortality due to heart disease, but the risks associated with yo-yo dieting have had much less research. For the study led by Rasla, the weight histories of 158,000 older, postmenopausal women were analysed. The women who were deemed to be yo-yo dieters - characterised as a cycle of gaining and losing 10 pounds or more - were also found to have a greater risk of coronary heart disease. Until further research is conducted, the message for now from Rasla is that "maintaining a stable body weight is best for overall health."
A new study has found the typical "social business diet", which consists heavily of red meats, sweet drinks, processed snacks and alcohol, has a detrimental effect on a person's heart. Unfortunately, it's a sign of the times that many individuals do not have, or at least don't think they have, enough time to sit down and eat a healthy meal. Instead, many people rely on grab-and-go food items that can be eaten on the road. However, according to a team of researchers from the Icahn School of Medicine at Mount Sinai in New York City, eating habits such as these up the risks of atherosclerosis - a slow, but steady clogging of one's arteries. In fact, eating out, snacking on the go, and excessive alcohol consumption is more unhealthy than the so-called Western diet. "This business diet is really very bad," said Dr. Valentin Fuster, a cardiology professor from Icahn. "It hits the arteries hard, and strongly contributes to cardiovascular disease risk, the world's number one killer," he added. The American Heart Association says that cardiovascular disease accounts for more than 17 million deaths across the world each year. Atherosclerosis occurs when plaque builds up in a person's arteries, and can raise their risk of blood clots, heart attacks, heart disease and stroke. If people want to lower their risk of cardiovascular problems in the future, they should minimise their consumption of red meat, sweets and alocohol, and increase their intake of vegetables, fruits, low-fat dairy products, whole grains, fish and nuts.
One hour of "brisk exercise" each day can offset the risk of early death for people who are desk-bound in their working lives, according to scientists. The study of physical activity - the results of which were published in The Lancet - analysed data from more than one million people to see how being inactive affects people's health. Watching TV was found to be worse than sitting at a desk. This is because of the associated habits that go with it, like snacking. However, even people who sit at a desk for eight hours a day because of their jobs can compensate by undertaking an hour of physical activity. In fact, the research found that desk-bound workers who were physically active had a significantly lower risk of death than people who weren't physically active and only sat for a few hours. At present, NHS guidelines recommend people do at least 150 minutes of exercise per week. The new research suggests that is insufficient for many. Being inactive has long been linked to conditions such as heart disease, diabetes and some cancers, and accounts for around 5.3 million deaths globally each year. For comparison, smoking accounts for around 5.1 million. Prof Ulf Ekelund, Lead author of the study, from the Norwegian School of Sports Sciences and Cambridge University, said that people don't even need to do sport or go the gym to exercise. "It’s OK doing some brisk walking, maybe in the morning, during lunchtime, after dinner in the evening. You can split it up over the day, but you need to do at least one hour," he said.
A new study has found that men are much more likely to suffer a cardiac arrest than women. In fact, around one in nine men will have their heart stop suddenly before the age of 70, compared to around one in 30 women. The study researchers said that by the age of 45, men have almost an 11% lifetime risk of sudden cardiac arrest. Women of the same age have just a 3% risk. According to Dr. Donald Lloyd-Jones, chair of preventive medicine at the Feinberg School of Medicine, in Chicago, approximately 450,000 Americans die from sudden cardiac arrest each year, and most never have any of the usual symptoms associated with a heart problem. He explained that because heart disease tends to develop earlier in men than in women, more serious screening for risk factors in the male population needs to be undertaken. Smoking, high cholesterol, high blood pressure and diabetes are all major cardiac arrest risk factors. "Know your numbers, especially your blood pressure, but also know your cholesterol or whether you have diabetes," said Dr. Lloyd-Jones. "At 50, men should also have a baseline electrocardiogram, which might reveal heart problems," he added. For the study, Dr. Lloyd-Jones and his colleagues analysed data on more than 5,200 men and women between the ages of 28 and 62 who took part in the long-running Framingham Heart Study.
Last year, we told you about the benefits to your gut of following a Mediterranean diet. Now, research published in the European Heart Journal says that a Mediterranean diet is better for people with heart disease than avoiding what's considered unhealthy in the so-called 'Western diet'. The new research shows that a Mediterranean diet, which includes large amounts of fruit, vegetables, fish and unrefined foods, can decrease the risk of stroke and heart attack in people who already have heart disease. Likewise, the study found that avoiding the unhealthy aspects of a Western diet, such as sweets, sugary drinks and deep-fried foods, also reduced a person's risk of cardiac issues. For the study, researchers from Auckland City Hospital at the University of Auckland in New Zealand analysed the dietary data of some 15,482 people with stable coronary artery disease across 39 countries globally. They found that fewer heart attacks and strokes were witnessed among those people who eat Mediterranean foods. In fact, for every 100 people eating Mediterranean foods, there were three fewer strokes, heart attacks or deaths than seen among the 100 people who consumed the least amount of healthy foods. Lead researcher Prof. Ralph Stewart said: "The research suggests we should place more emphasis on encouraging people with heart disease to eat more healthy foods, and perhaps focus less on avoiding unhealthy foods."
From 1999 to 2014, rates of severe obesity among kids in the US climbed, highlighting that the issue still very much continues to plague American children today. Examining national data over the 15-year period, researchers found that a third of children in the US aged between two and 19 were overweight. They also found, more worryingly, that nearly a quarter were obese and two per cent severely obese. Lead researcher Asheley Skinner, from the Duke Clinical Research Institute in Durham, N.C., said: "Despite other recent reports, all categories of obesity have increased from 1999 to 2014, and there is no evidence of a decline in the last few years." Skinner added that there are currently 4.5 million obese kids in the US who urgently need treatment because they have a heightened risk of developing type 2 diabetes, heart disease and cancer, compared with children their age who are not obese. "Unless we make big changes on a national level, we're not going to see huge changes in obesity," Skinner said. By changing school lunches; increasing opportunities for physical activity, and allowing parents access to more healthy food options, the problem of childhood obesity can be tackled head-on, according to Skinner. The study, the results of which were published in the journal Obesity, also found that rates of obesity were higher in black and hispanic children, suggesting these groups need particular help going forward to combat the problem.
New research from South Korea shows that a nut-rich diet can reduce a person's risk of developing colon cancer. It adds to the list of health benefits already associated with nuts, such as a reduced risk of heart disease, stroke and obesity. According to the findings of the research, which was conducted by a team at Seoul National University College of Medicine, eating a serving of nuts three or more times per week appeared to have a big impact on risk. This reduction was noted in both men and women. For the study, a serving of nuts was considered to be 15g, which is actually significantly smaller than serving sizes found across the world. And while many types of nuts were used for the study, the majority of participants consumed peanuts - presumably because of their availability in South Korea. Men who ate three or more servings of nuts every week were found to have a 69% lower risk of colon cancer than those who didn't. The risk reduction in women was even greater, with 81% found to have a lower risk. Also worthy of note is the fact that the researchers discovered that nut consumption was associated with a reduced risk across all of the different areas where colon cancer is seen and different types of colon cancer. So if nuts aren't a part of your regular diet, perhaps they should be...
A new study has revealed that heart attack victims in the United States are becoming younger and fatter. Over the past two decades alone, the average age of people suffering the deadliest heart attacks has fallen from 64 to 60, and obesity has been implicated in 40% of the most severe, according to researchers at Cleveland Clinic, Ohio. In addition, heart attack sufferers nowadays are more likely to be smokers and people with high blood pressure, diabetes and chronic obstructive pulmonary disease (COPD), compared to 20 years ago. It's a reality that is raising alarm bells. "Lifestyle changes to reduce weight, eat right, exercise and quit smoking are critical for prevention of heart attack," said senior researcher Dr. Samir Kapadia, an an interventional cardiologist in the Cleveland Clinic Department of Cardiovascular Medicine at Cleveland Clinic. Dr. Kapadia added that the responsibility for making these lifestyle changes should be shared between the patient and their medical doctor, and the issue discussed at routine checkups. The study focused on analysing heart disease risk factors among more than 3,900 patients; all of whom had been treated for an ST-elevation myocardial infarction (STEMI). One of the most severe types of heart attack, STEMIs often result in disability or death and occur when the heart's main artery is completely blocked by plaque. The results of the study are scheduled to be presented on April 4 at the American College of Cardiology's annual meeting in Chicago.