If you’re looking to lose some weight, eating earlier in the day and intermittently fasting could help, new research suggests. According to a paper published in the journal Obesity, the timing of meals and intermittent fasting influences metabolism, which can have an impact on weight loss. Researchers discovered this following a trial involving 11 men and women, all of who were in good health, aged between 25 and 45 years and carrying some excess weight. The trial participants were split into two groups: one who ate breakfast at 08:00 and then ate their last meal of the day at 14:00, and another who ate breakfast at 08:00 and had their last meal of the day at 20:00. Both groups ate the same meals each day. At the end of the trial, participants underwent a battery of tests in a respiratory chamber to assess their metabolism. The number of calories, fat, carbohydrates and proteins burned were all measured. It was revealed that the participants who ate their last meal of the day at 14:00 and, therefore, fasted longer overnight, burned more fat than the other group. They also had lower levels of the hunger hormone ghrelin. “Eating in sync with circadian rhythms by eating early in the daytime appears to reduce body weight and improve metabolic health,” the authors of the paper wrote.
Some of the warning signs often associated with type-2 diabetes can be detected years before the disease is actually diagnosed, researchers say. A study found factors such as insulin resistance and elevated blood sugar levels were seen in people years prior to them developing pre-diabetes – a typical pre-cursor to the type-2 form of the disease. The authors of the Japanese study say their findings suggest that diabetes treatment should begin much earlier in life. For the study, conducted over an 11-year period, the researchers followed a group of 27,000 people who were not diabetic and aged between 30 and 50. The individuals were tracked until they either (a) got diagnosed with type-2 diabetes; (b) got diagnosed with pre-diabetes; or (c) the end of 2016 was reached. During the study, 1,067 new cases of type-2 diabetes were diagnosed. The interesting part is that these people showed warning signs, such as insulin resistance and higher fasting blood sugar levels, up to 10 years prior. Similar warning signs were also seen in those that went on to develop pre-diabetes. So, this suggests that type-2 diabetes could actually be detected up to 20 years before a diagnosis occurs. This is because people who develop type-2 diabetes usually get pre-diabetes first. Dr Hiroyuki Sagesaka, from Aizawa Hospital in Matsumoto, Japan, who led the research, said: “Because trials of prevention in people with pre-diabetes seem to be less successful over long-term follow-up, we may need to intervene much earlier than the pre-diabetes stage to prevent progression to full blown diabetes. “A much earlier intervention trail, either drug or lifestyle-related, is warranted.” [Related reading: Diabetes is actually five diseases, not two]
Intermittent fasting is something that’s become more popular in recent times with people looking to shed a few kilograms and now new research shows that it could actually have ‘profound health benefits’. In addition to helping people lose weight, intermittent fasting, according to the research by a team at the University Of Florida College Of Medicine, can also slow down aging and disease. The human body runs on glucose, which it gets from the food we eat. However, periods of fasting force the body to find an alternative energy source. Our bodies begin to convert body fat into fatty acids which are easily absorbed by our blood. Molecules called ketones are then produced from the fatty acids, which our bodies use as a new source of energy. Stephen Anton, a researcher from the University Of Florida College Of Medicine in Gainesville, refers to this process as "flipping the metabolic switch". He says "this switch can happen after a certain period of time fasting. It's a gradation in which your metabolism overtime shifts to use higher and higher amounts of ketones for energy”. Having reviewed numerous studies that focused on the mechanisms and benefits of intermittent fasting, Anton and his team discovered that not only did intermittent fasters experience significant weight loss, they did not lose lean tissue, such as organ tissue, muscular tissue, and bone tissue, which allow our bodies to continue functioning well and could help prolong our lifespans.
Whether you call them love handles or muffin tops, the areas of built up fat that can appear above your waistline are something that many people would love to be able to easily get rid of. A new patch developed by scientists in the US could provide the easy fix people have been looking for. The novel patch delivers fat-browning drugs directly into the areas of fat and converts "bad" white fat into "good" brown fat - not only reducing the amount of excess fat, but also lowering fasting blood glucose levels. Having too much white fat - particularly around the abdominal region - can raise the risk of several health problems, including diabetes and heart disease. So far, the patches have only been trialled on mice, but it’s hoped that they can be developed for human use in the future. Study co-leader Li Qiang, Ph.D., from the Columbia University Medical Center in New York City, said the patches could offer a great alternative to existing drugs that promote fat browning. Their non-invasive nature can reduce side effects. "The nanoparticles were designed to effectively hold the drug and then gradually collapse, releasing it into nearby tissue in a sustained way instead of spreading the drug throughout the body quickly," says study co-leader Zhen Gu, Ph.D., from the University of North Carolina at Chapel Hill and North Carolina State University in Raleigh.
If you have decided that you are going to have a surgical procedure then there are certain ways in which you must prepare for your surgery. Travel arrangements – if you opt for medical tourism then your travel arrangements obviously become a bit more complicated as you need to consider how you will travel to and from the country you have chosen. With France Surgery these travel arrangements are arranged on your behalf by the France Surgery team. Your travel to and from the hospital will also be arranged for you. Pre-operative assessment - 1-2 days before the procedure you will have an assessment to ensure that everything is ready for the surgery and that you are healthy enough to undergo the procedure. Hospital bag – France Surgery will provide you with all the information you need about what to take to hospital with you. Ensure that you have everything you need in order to make your stay more comfortable. Adhere to any advice you have been given – after your assessment you will be informed of anything you must or must not do, e.g. fasting, taking medication or stopping medication. Ensure you follow all of these guidelines. Photo credit: France Surgery