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New ovarian cancer test is a ‘potential game-changer’

27/11/2018

Ovarian cancer treatment is much more effective if it’s administered during the early stages of the disease. In fact, when ovarian cancer is diagnosed early, approximately 94% of patients have a good prognosis post-treatment. However, the reality is that relatively few cases (about 20%) of ovarian cancer are diagnosed early, which makes treatment less effective. But a newly developed blood test could change this. Beyong a full pelvic exam, medical professionals, at present, have two options when it comes to testing for ovarian cancer: a transvaginal ultrasound and a cancer antigen 125 (CA 125) blood test. Unfortunately, both have significant limitations. For example, while the ultrasound can detect growths, it cannot determine whether they are cancerous. The CA 125 test looks for a specific ovarian cancer marker, but people with unrelated conditions also have high levels of this particular antigen. These limitations of the existing tests are one of the driving forces behind the development of the new blood test. The new test, developed by a team from Griffith University and the University of Adelaide (both in Australia), looks for telltale sugars associated with ovarian cancer cells. According to the findings of the team’s study, the new blood test detected large levels of the sugars in 90% of people with stage 1 ovarian cancer and 100% of people with later stage ovarian cancer. Moreover, the test detected none of the telltale sugars in healthy participants. Prof. James Paton, one of the study authors, said the test is a huge step toward diagnosing ovarian cancer in its early stages. “Ovarian cancer is notoriously difficult to detect in its early stages, when there are more options for treatment and survival rates are better. Our new test is therefore a potential game-changer,” he said.

NHS England to introduce one-stop cancer shops

05/04/2018

NHS England is in the process of introducing ‘one-stop cancer shops’ across the country, the aim of which is to afford quicker diagnoses for patients. At present, patients often face delays as they are sent for several tests to check for different forms of the illness. Despite cancer survival rates having increased over recent decades, patients who do not display obvious signs of cancer often face treatment delays. For example, individuals who have experienced unexplained weight loss, reduced appetite or abdominal pain can be referred several times for different tests, which delays valuable opportunities to begin treatment. The approach NHS England is now adopting was first introduced in Denmark and allows patients to undergo all the necessary tests under one roof. Cally Palmer, national director for cancer at NHS England, said: "Early diagnosis is crucial to saving lives and providing peace of mind for patients, which is why we are driving forward plans to revolutionise our approach to cancer in this country. "These new one-stop shops represent a real step change in the way people with unclear symptoms are identified, diagnosed and treated." The bottom line is that the rapid diagnosis and subsequent fast treatment of cancer is vital for saving lives. Initially, there will be 10 such centres spread across England at the following locations: Royal Free Hospital, London North Middlesex Hospital, London, University College Hospitals London Southend University Hospital Queens Hospital, Romford St James University Hospital, Leeds Airedale General Hospital, West Yorkshire University Hospital, South Manchester Royal Oldham Hospital, Greater Manchester Churchill Hospital, Oxford More centres will be added if the project is a success.

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